Radial keratoneuritis as a presenting sign in Acanthamoeba keratitis.
Radial keratoneuritis as a presenting sign in Acanthamoeba keratitis.
复制标题
放射状角膜神经炎是棘阿米巴角膜炎的症状。
DOI：
10.1016/s0161-6420(86)33572-3
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发表时间：
1986
期刊：
影响因子：
13.7
通讯作者：
Robin,JB
中科院分区：
文献类型：
--
作者：
Moore,MB;McCulley,JP;Kaufman,HE;Robin,JB
三名佩戴软性隐形眼镜的近视患者出现单侧棘阿米巴角膜炎，表现为沿着角膜神经分布的异常浸润。这些浸润发现于中基质，从中央旁开始，并以放射状延伸至角膜缘。这些浸润物上覆盖的上皮是完整的。在两名患者中，中央上皮具有点状、几乎树突状的外观，导致单纯疱疹性角膜炎的误诊。两名患者的角膜刮片培养物和一名患者的角膜活检培养物（其中包括推测的神经受累区域）培养出了棘阿米巴。所有三名患者均使用自制盐溶液（将盐片溶解在蒸馏水中）。在一名患者的隐形眼镜盒溶液中发现了棘阿米巴。根据我们最近的经验，另外两名阿米巴患者的蒸馏水瓶以及由蒸馏水和盐片制成的盐水溶液中也发现了棘阿米巴原虫。角膜炎。蒸馏水虽然不是无菌的，但已被证明是一种可以避免的 A 来源。隐形眼镜佩戴者的角膜炎。
Three myopic patients who wore soft contact lenses developed unilateralAcanthamoeba keratitisthat presented with unusual infiltrates that appeared to be located along the corneal nerves. These infiltrates were found in the midstroma, beginning paracentrally, and extending to the limbus in a radial pattern. The epithelium overlying these infiltrates was intact. In two patients, the central epithelium had a stippled, almost dendritiform appearance leading to the misdiagnosis of herpes simplex keratitis. Cultures from corneal scrapings of two patients and cultures of a corneal biopsy from one patient, which included an area of presumed neural involvement, grew Acanthamoebae. All three patients used homemade saline solutions (salt tablets dissolved in distilled water). In one patient, Acanthamoebae were found in the contact lens case solution. In our recent experience, Acanthamoebae have also been found in the distilled water bottle and the saline solution made from distilled water and salt tablets in two additional patients withA. keratitis. Distilled water, which is not sterile, has proven to be one potentially avoidable source ofA. keratitisin contact lens wearers.