Effects of body region and time on hair cortisol concentrations in chimpanzees (Pan troglodytes)
Effects of body region and time on hair cortisol concentrations in chimpanzees (Pan troglodytes)
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DOI：
10.1016/j.ygcen.2015.09.022
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发表时间：
2015-11-01
影响因子：
2.7
通讯作者：
van Schalk, Carel P.
中科院分区：
文献类型：
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作者：
Carlitz, Esther H. D.;Kirschbaum, Clemens;van Schalk, Carel P.
头发皮质醇浓度（HCC）越来越被认为是全身皮质醇分泌的综合指标。然而，我们对动物肝癌的混杂影响仍然知之甚少。因此，本研究使用来自半野生和动物园活体黑猩猩的毛发来研究（1）HCC的个体内变异性（身体区域效应），以及（2）HCC沿毛干的稳定性（传统上称为冲刷效应）。我们的结果表明，某些身体区域之间的绝对 HCC 差异很大，但因子分析显示，这些 HCC 差异主要归因于一个共同的方差来源。因此，来自身体各个部位的毛发提供相似的生物信号并且可以混合，尽管以较低的信噪比为代价。关于潜在的潜在机制，我们研究了通过一只黑猩猩的热图像观察到的皮肤血流。我们发现一般 HCC 模式反映在该个体四分之三身体区域中观察到的表面体温差异。在一组单独的样本中，我们发现了第一个证据，表明正如在人类中观察到的那样，沿着毛干的系统性皮质醇减少也存在于黑猩猩的毛发中。这种影响在半野生黑猩猩中比在动物园黑猩猩中更为明显，可能是因为更多地暴露在周围的天气条件下。 (C) 2015 Elsevier Inc. 保留所有权利。
Hair cortisol concentrations (HCC) are increasingly recognized as an integrated measure of the systemic cortisol secretion. Yet, we still know very little about confounding effects on HCC in animals. The present study therefore used hair from semi-wild and zoo living chimpanzees to investigate (1) intra-individual variability of HCC (body-region effect), and (2) the stability of HCC along the hair shaft (traditionally called the washout effect). Our results indicate that absolute HCC varied substantially between certain body regions, but a factor analysis revealed that these HCC differences were mainly attributable to one common source of variance. Thus, hair from all body regions provides similar biological signals and can be mixed, albeit at the cost of a lower signal-to-noise ratio. With regard to potential underlying mechanisms, we studied skin blood flow, as observed through thermal images from one chimpanzee. We found the general HCC pattern was reflected in differences in surface body temperature observed in this individual in three out of four body regions. In a separate set of samples, we found first evidence to suggest that the systematic cortisol decrease along the hair shaft, as observed in humans, is also present in chimpanzee hair. The effect was more pronounced in semi-wild than in zoo chimpanzees presumably due to more exposure to ambient weather conditions. (C) 2015 Elsevier Inc. All rights reserved.