Healing of Full-Thickness Murine Skin Wounds Containing Nanofibers Using Splints for Efficient Reepithelialization and to Avoid Contracture.
Healing of Full-Thickness Murine Skin Wounds Containing Nanofibers Using Splints for Efficient Reepithelialization and to Avoid Contracture.
复制标题
使用夹板治愈含有纳米纤维的全层小鼠皮肤伤口,以实现有效的上皮再生并避免挛缩。
DOI:
10.1007/978-1-0716-0655-1_10
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发表时间:
2020
期刊:
影响因子:
--
通讯作者:
Ganguli-Indra,Gitali
中科院分区:
文献类型:
--
作者:
Bhattacharya,Nilika;Indra,ArupK;Ganguli-Indra,Gitali
Wound healing process is the outcome of a series of actions and combined with collaborative process involving concerted efforts of multiple cell types. The dynamic series of events constituting each of these overlapping rather than discrete stages of wound healing increases its complexity and the necessity to understand it. The contrasting mechanisms of wound healing employed by mouse (via wound contraction) and humans (via reepithelialization) puts forth the need of a model closely mimicking human wound-healing and hence comes the applicability of the mouse excisional wound splinting model. Use of silicone-based splints has demonstrated their effectiveness in aptly resembling the human reepithelialization mediated wound healing by preventing contraction during healing. The rising popularity of nanofiber-based treatments for wound healing through sustained release of factors/molecules promoting wound closure can be potentially implemented in association with this model to determine its efficacy in wound management in a more humanized way.
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DOI:
--
发表时间:
1987
期刊:
影响因子:
--
作者:
F. L. Moore
通讯作者:
F. L. Moore
影响因子:
2.9
作者:
B. J. Ward;H. Charlton
通讯作者:
H. Charlton
影响因子:
2.5
作者:
P. Verrell
通讯作者:
P. Verrell
影响因子:
4.8
作者:
S. Salthe;J. S. Mecham
通讯作者:
J. S. Mecham
影响因子:
2.7
作者:
Zoeller,RT;Moore,FL
通讯作者:
Moore,FL