Identification of three isoforms for mitochondrial adenine nucleotide translocator in the pufferfish Takifugu rubripes
Identification of three isoforms for mitochondrial adenine nucleotide translocator in the pufferfish Takifugu rubripes
复制标题
DOI：
10.1016/j.mito.2005.01.003
复制
发表时间：
2005-06-01
期刊：
影响因子：
4.4
通讯作者：
Watabe, S
中科院分区：
文献类型：
--
作者：
Itoi, S;Misaki, R;Watabe, S
从红鳍东方鲀（Takifugu rubripes）基因组数据库中提取了3个腺嘌呤核苷酸转运子（ANT）基因，并在体内分离了相应的cDNA。系统发育分析结果表明，scaffold_254上的ANT基因与哺乳动物的ANT 1相对应，而scaffold_6和scaffold_598上的ANT基因与哺乳动物的ANT 3相对应。由scaffold_6编码的ANT基因在各种组织中普遍表达，而由scaffold_254和scaffold_598编码的ANT基因分别主要在骨骼肌和心脏中表达。(C)2005年Elsevier B.V.和线粒体研究学会。All rights reserved.
Three adenine nucleotide translocator (ANT) genes were identified through in silico data mining of the Fugu genome database along with isolation of their corresponding cDNAs in vivo from the pufferfish (Takifugu rubripes). As a result of phylogenetic analysis, the ANT gene on scaffold_254 corresponded to mammalian ANT1, whereas both of those on scaffold_6 and scaffold_598 to mammalian ANT3. The ANT gene encoded by scaffold_6 was expressed ubiquitously in various tissues, whereas the ANT genes encoded by scaffold_254 and scaffold_598 were predominantly expressed in skeletal muscle and heart, respectively. (C) 2005 Elsevier B.V. and Mitochondria Research Society. All rights reserved.