The effect of brain tumour laterality on anxiety levels among neurosurgical patients
The effect of brain tumour laterality on anxiety levels among neurosurgical patients
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DOI：
10.1136/jnnp.74.9.1278
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发表时间：
2003-09-01
影响因子：
11
通讯作者：
Räsänen, P
中科院分区：
文献类型：
--
作者：
Mainio, A;Hakko, H;Räsänen, P
目的：本研究的目的是调查原发性脑肿瘤患者的焦虑水平，并分析肿瘤偏侧性和组织学对焦虑水平的影响。复发测量术前评估，3个月，一年后operation.Methods：研究人群包括101例原发性脑肿瘤的患者在北方芬兰的Kazakhstan和同质人口。术前用CT或MRI检查患者以确定肿瘤的位置。根据WHO分类定义肿瘤的组织学。焦虑的水平获得冠脆经验指数（CCEI）scale.Results：在右半球的肿瘤的患者有统计学显着较高的平均焦虑评分相比，在左半球的肿瘤手术前的肿瘤的患者。手术切除肿瘤后三个月和一年，右半球肿瘤患者的焦虑水平下降。在左半球有肿瘤的患者中没有发现相应的下降。根据肿瘤组织学的偏侧性，右半球胶质瘤的男性和女性患者的焦虑水平显着下降，但相应的下降在右半球脑膜瘤的女性患者中并不显着。焦虑水平的下降，没有发现在左半球的胶质瘤或脑膜瘤患者的随访measurement.Conclusions：原发性脑肿瘤在右半球与焦虑症状。焦虑的偏侧化似乎反映了两个半球的分化。右侧肿瘤手术后焦虑水平下降，接近一般人群。在未来的研究中，右半球胶质瘤对焦虑症状的影响值得特别关注。
Objectives: The aim of this study was to investigate the level of anxiety in patients with a primary brain tumour and to analyse the effect of tumour laterality and histology on the level of anxiety. Recurrent measurements were assessed preoperatively, three months, and one year after operation.Methods: The study population consisted of 101 patients with a primary brain tumour from unselected and homogeneous population in northern Finland. The patients were studied preoperatively with CT or MRI to determine the location of the tumour. The histology of the tumour was defined according to WHO classification. The level of anxiety was obtained by Crown-Crisp Experiential Index (CCEI) scale.Results: The patients with a tumour in the right hemisphere had statistically significantly higher mean anxiety scores compared to the patients with a tumour in the left hemisphere before surgery of the tumour. By three months and by one year after surgical resection of the tumour, the level of anxiety declined in patients with a tumour in the right hemisphere. A corresponding decline was not found in patients with a tumour in the left hemisphere. According to laterality by tumour histology, the level of anxiety decreased significantly in male and female patients with a glioma in the right hemisphere, but a corresponding decline was not significant in the female patients with a meningioma in the right hemisphere. Decreased level of anxiety was not found in patients with gliomas or meningiomas in the left hemisphere by follow up measurements.Conclusions: Primary brain tumour in right hemisphere is associated with anxiety symptoms. The laterality of anxiety seems to reflect the differentiation of the two hemispheres. The level of anxiety declined after operation of right tumour, approaching that of the general population. The effect of right hemisphere gliomas on anxiety symptoms deserves special attention in future research.