Two Notorious Nodes: a Critical Examination of Relaxed Molecular Clock Age Estimates of the Bilaterian Animals and Placental Mammals.
Two Notorious Nodes: a Critical Examination of Relaxed Molecular Clock Age Estimates of the Bilaterian Animals and Placental Mammals.
复制标题
两个臭名昭著的节点：对两侧对称动物和胎盘哺乳动物的宽松分子钟年龄估计的严格检查。
DOI：
10.1093/sysbio/syad057
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发表时间：
2023
影响因子：
6.5
通讯作者：
Budd GE
中科院分区：
文献类型：
--
作者：
Budd GE
流行的放松时钟贝叶斯推断的分支起源的时间产生了几个最近的出版物与焦点的结果相当老的化石的分支的问题。在这里，我们批判性地研究两个这样的分支：动物（重点放在两侧）和哺乳动物（重点放在胎盘）。每一个例子都显示了一组特征性的病理学，尽管有很多评论，但很少被纠正。我们的结论是，在这种情况下，分子钟分析提供任何证据的起源分支更深的化石记录所建议的。此外，这两个分支都有其他特征（包括，在胎盘哺乳动物的情况下，接近大规模灭绝），使我们能够对它们起源的时间产生精确的预期。因此，在这些情况下，化石记录可以为分子钟方法提供强有力的测试，以及为什么它会误入歧途，我们有充分的理由认为这些问题是普遍的。【寒武纪大爆发;哺乳动物进化;分子钟。】
The popularity of relaxed clock Bayesian inference of clade origin timings has generated several recent publications with focal results considerably older than the fossils of the clades in question. Here, we critically examine two such clades: the animals (with a focus on the bilaterians) and the mammals (with a focus on the placentals). Each example displays a set of characteristic pathologies which, although much commented on, are rarely corrected for. We conclude that in neither case does the molecular clock analysis provide any evidence for an origin of the clade deeper than what is suggested by the fossil record. In addition, both these clades have other features (including, in the case of the placental mammals, proximity to a large mass extinction) that allow us to generate precise expectations of the timings of their origins. Thus, in these instances, the fossil record can provide a powerful test of molecular clock methodology, and why it goes astray, and we have every reason to think these problems are general. [Cambrian explosion; mammalian evolution; molecular clocks.]