Induction of lignans and phenolic compounds in cell culture of Linum album by culture filtrate of Fusarium graminearum
Induction of lignans and phenolic compounds in cell culture of Linum album by culture filtrate of Fusarium graminearum
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DOI：
10.1080/17429145.2013.846419
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发表时间：
2014-01
影响因子：
3.2
通讯作者：
Jaleh Tahsili;M. Sharifi;N. Safaie;Sedigheh Esmaeilzadeh-Bahabadi;M. Behmanesh
中科院分区：
文献类型：
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作者：
Jaleh Tahsili;M. Sharifi;N. Safaie;Sedigheh Esmaeilzadeh-Bahabadi;M. Behmanesh
亚麻的细胞悬浮培养。已报道产生抗癌鬼臼毒素及其相关的木脂素。本文研究了禾谷镰刀菌培养滤液对禾谷镰刀菌生长的影响，以及对禾谷镰刀菌中木脂素和酚类物质的影响。白细胞培养预培养7天后，用1%（v/v）的培养滤液处理细胞。细胞生长减少，而光敏白毒素和落叶松树脂酚的生产刺激达到最大值0.0187毫克/克鲜重（FW）和0.0136毫克/克FW处理后5天，分别。此外，我们的研究结果提供了证据，F。禾谷镰刀菌对苯丙氨酸解氨酶活性和酚类化合物有效。
Cell suspension cultures of Linum album Kotschy ex Boiss. have been reported to produce anticancer podophyllotoxin and its related lignans. In the present study, we investigated the effect of culture filtrate of Fusarium graminearumon growth, and lignan and phenolic compounds in L. album cell culture. After 7 days of pre-culture, the cells were treated with 1% (v/v) of the culture filtrate. Cell growth was reduced, while phodophyllotoxin and lariciresinol production was stimulated reaching a maximum 0.0187 mg/g fresh weight (FW) and 0.0136 mg/g FW 5 days after the treatment, respectively. Also, our results provide evidence that the culture filtrate of F. graminearum can be effective on phenylalanine ammonia-lyase activity and phenolic compounds.