Design and simulation of a novel electrostatic peristaltic micromachined pump for drug delivery applications
Design and simulation of a novel electrostatic peristaltic micromachined pump for drug delivery applications
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DOI：
10.1016/j.sna.2004.06.025
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发表时间：
2005-01-14
影响因子：
4.6
通讯作者：
Abbaspour-Sani, E
中科院分区：
文献类型：
--
作者：
Teymoori, MM;Abbaspour-Sani, E
设计并仿真了一种新型的医用静电微机械泵。微泵的结构包括一个输入和一个输出端口，三个膜，三个主动膜阀，微通道，和三个静电驱动系统。所提出的微泵的泵送机制是基于蠕动运动，具有一些优点，如高可控性和精度，比其他机制，使其适合于用于医疗应用。由于静电致动具有体积小等优点，被广泛应用于薄膜阀的偏转控制，用主动薄膜阀代替被动单向阀，解决了阀门堵塞和泄漏等问题。所设计的微泵满足所有医疗药物输送要求，如药物相容性，流量可控性，自吸，小芯片尺寸，低功耗。所设计的微型泵的流速为9.1 μ l穆尔/分钟，这非常适合于药物输送应用，例如化疗。所设计的微泵的总尺寸为7 mm x 4 mm x 1 mm，比其他蠕动式微泵小。假设零残余应力，低驱动电压，和小尺寸是我们的设计的主要优点。利用ANSYS5.7软件对所设计的微泵进行了有限元模拟。(C)2004 Elsevier B. V.保留所有权利。
A novel electrostatic micromachined pump for medical applications is designed and simulated. The proposed structure for the micropump consists of an input and an output port, three membranes, three active membrane valves, microchannels, and three electrostatic actuation systems. Pumping mechanism of the proposed micropump is based on the peristaltic motion that has some advantages, such as high controllability and precision, over the other mechanism that makes it suitable to be used for the medical applications. Electrostatic actuation has been employed for the deflection of the membranes because of its benefits, such as the smaller size of the device in comparison with the other types, especially piezoelectric counterpart and so on. Employing active membrane valves instead of passive check valves resolves some of the problems, such as valve clogging and leakage. The designed micropump satisfies all medical drug delivery requirements, such as drug compatibility, flow rate controllability, self-priming, small chip size, and low power consumption. The flow rate of the designed micropump is 9.1 mul/min which is quite suitable for drug delivery applications, such as chemotherapy. Total size of the designed micropump is 7 mm x 4 mm x 1 mm, which is smaller than the other peristaltic counterpart micropumps. Assuming zero residual stress, low actuation voltage, and small size are the main advantages of our design. The designed micropump is simulated by the finite element method, using the ANSYS 5.7 software. (C) 2004 Elsevier B.V. All rights reserved.