Advancing the global public health agenda for NAFLD: a consensus statement
Advancing the global public health agenda for NAFLD: a consensus statement
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DOI：
10.1038/s41575-021-00523-4
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发表时间：
2021-10-27
影响因子：
65.1
通讯作者：
Zelber-Sagi, Shira
中科院分区：
文献类型：
--
作者：
Lazarus, Jeffrey, V;Mark, Henry E.;Zelber-Sagi, Shira
非酒精性脂肪性肝病（NAFLD）是一种潜在的严重肝病，影响全球约四分之一的成年人口，造成巨大的健康不良负担，具有广泛的社会和经济影响。它是一种多系统疾病，被认为是代谢综合征的肝脏成分。与其他高度流行的疾病不同，NAFLD很少受到全球公共卫生界的关注。卫生系统和公共卫生对NAFLD的反应一直很薄弱和分散，尽管NAFLD普遍存在，但在肝病学和胃肠病学之外，NAFLD在很大程度上是未知的。只有一个新生的全球公共卫生运动解决NAFLD，几乎所有国家和国际非传染性疾病，包括肥胖症的战略和政策都没有这种疾病。在这项全球性的德尔菲研究中，一个多学科的专家小组制定了共识声明和建议，一个更大的合作者小组经过三轮审查，直到达成共识。由此产生的共识声明和建议涉及广泛的议题-从流行病学、认识、护理和治疗到公共卫生政策和领导-对决策者、保健从业人员、民间社会团体、研究机构和受影响人口具有普遍意义。非酒精性脂肪肝（NAFLD）是一种潜在的严重肝脏疾病，在全球范围内造成巨大负担。在这份共识声明中，一个全球多学科专家小组制定了共识声明和建议，涉及NAFLD的广泛主题，以提高认识和促进行动。
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attention from the global public health community. Health system and public health responses to NAFLD have been weak and fragmented, and, despite its pervasiveness, NAFLD is largely unknown outside hepatology and gastroenterology. There is only a nascent global public health movement addressing NAFLD, and the disease is absent from nearly all national and international strategies and policies for non-communicable diseases, including obesity. In this global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved. The resulting consensus statements and recommendations address a broad range of topics - from epidemiology, awareness, care and treatment to public health policies and leadership - that have general relevance for policy-makers, health-care practitioners, civil society groups, research institutions and affected populations. These recommendations should provide a strong foundation for a comprehensive public health response to NAFLD.Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease with a substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts develop consensus statements and recommendations addressing a broad range of topics on NAFLD to raise awareness and spur action.