Multicenter Evaluation of Implantable Cardioverter Defibrillator Testing after Implant: The Post Implant Testing Study (PITS)
Multicenter Evaluation of Implantable Cardioverter Defibrillator Testing after Implant: The Post Implant Testing Study (PITS)
复制标题
植入式心脏复律除颤器植入后测试的多中心评估：植入后测试研究 (PITS)
DOI：
10.1111/j.1540-8159.1999.tb00409.x
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
S. Vlay
中科院分区：
文献类型：
--
作者：
Craig M. Brodsky;Fang Chang;S. Vlay
为了重新评估植入式心律转复除颤器（ICD）的功能，许多电生理中心在植入时进行初次测试后进行第二次测试。一项前瞻性多中心研究评价了常规植入后除颤器测试的必要性和产量。从31个中心收集了843个植入后除颤器测试的结果。对764例诱发成功的常规试验结果进行分析。检查的变量包括患者年龄、心律失常、基础心脏病、左心室射血分数、除颤器年龄、ICD的品牌和型号、电极系统、除颤阈值、极性和波形。总失败率为3.1%（24/764）。在植入后365天后测试的装置的失效率往往高于在第一个月或接下来的11个月内测试的装置（分别为6.5%、3.0%、2.3%，P = 0.374）。左室射血分数< 40%的患者失败率高于射血分数高者（3.8% vs 2.0%，P = 0.167）。这些趋势未达到统计学显著性。没有其他基线特征与较高的失败率相关。ICD的常规测试显示总体故障率为3.1%。虽然发生率很低，但除颤器故障使患者处于心脏性猝死的高风险中。由于该人群中的任何失败都与心脏性猝死的高风险相关，因此常规除颤器测试可能是合理的。
To reassess the function of the implantable cardioverter defibrillator (ICD) many electrophysiology centers perform a second test after the initial test at implant. A prospective multicenter study evaluated the necessity and yield of routine postimplant defibrillator testing. The results of 843 postimplant defibrillator tests were collected from 31 centers. The 764 routine tests in which ventricular fibrillation was successfully induced were analyzed. Variables examined included patient age, presenting arrhythmia, underlying heart disease, left ventricular ejection fraction, defibrillator age, make and model of ICD, electrode system, defibrillation threshold, polarity, and waveform. The overall failure rate was 3.1% (24/764). Units tested later than 365 days after implant tended to have a higher failure rate than those tested within the first month or the next eleven months (6.5%, 3.0%, 2.3%, respectively, P = 0.374). The failure rate was higher in patients with left ventricular ejection fraction < 40% than those with higher ejection fractions (3.8% vs 2.0%, P = 0.167). These trends did not reach statistical significance. No other baseline characteristic was associated with higher failure rates. Routine testing of ICDs reveals an overall failure rate of 3.1%. While the rate was low, defibrillator failure places the patient at high risk for sudden cardiac death. As any failure in this population is associated with a high risk of sudden cardiac death, routine defibrillator testing may be justified.
对从近乎致命的室性心律失常中复苏的患者进行抗心律失常药物治疗与植入式除颤器的比较。
DOI：
10.1056/nejm199711273372202
发表时间：
1997
期刊：
The New England journal of medicine
影响因子：
--
作者：
AntiarrhythmicsversusImplantableDefibrillators(AVID)Investigators
通讯作者：
AntiarrhythmicsversusImplantableDefibrillators(AVID)Investigators