Comparison of subcutaneous and intravenous continuous glucose monitoring accuracy in an operating room and an intensive care unit
Comparison of subcutaneous and intravenous continuous glucose monitoring accuracy in an operating room and an intensive care unit
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手术室和重症监护病房皮下和静脉连续血糖监测准确性的比较
DOI：
10.1007/s10047-015-0877-2
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发表时间：
2016
期刊：
影响因子：
1.3
通讯作者：
Hanazaki K
中科院分区：
文献类型：
--
作者：
Munekage M;Yatabe T;Sakaguchi M;Kitagawa H;Tamura T;Namikawa T;Hanazaki K
虽然我们已经使用静脉连续血糖监测仪进行血糖管理，但先前的一项研究报道，皮下连续血糖监测仪也可用于危重患者。本研究的目的是比较皮下和静脉连续血糖监测仪。这是一项观察性试验（UMIN-CTR, ID:000013338）。我们纳入了在肝胆胰手术后入住重症监护病房（ICU）的患者。从手术开始到ICU出院，使用静脉连续监护仪STG-55 （Nikkiso, Tokyo, Japan）和皮下连续监护仪iPro2 （Medtronic Japan, Tokyo, Japan）进行持续血糖测量。STG-55实时测量血糖水平，iPro2每5分钟测量一次。我们使用Bland-Altman图和回归分析比较每5分钟使用两个设备获得的葡萄糖水平。15例共3592份比较样本进行分析。使用STG-55测量的平均血糖水平为139±21 mg/dl，使用iPro2测量的平均血糖水平为144±31 mg/dl。线性回归线方程为：= 0.225x+ 106。决定系数为0.11，f检验显著性水平为asp< 0.01。差异的平均值为- 5.2 mg/dl， 95%的一致性限为- 67至+ 57 mg/dl。误差率为44%。总之，目前的研究表明，在手术或ICU住院期间，皮下和静脉连续血糖监测并没有高度相关。
Although we have used an intravenous continuous glucose monitor for blood glucose management, a previous study reported that a subcutaneous continuous glucose monitor was also reliable for use in critically ill patients. The aim of this study was to compare the subcutaneous and intravenous continuous glucose monitors. This was an observational trial (UMIN-CTR, ID:000013338). We included patients who were admitted to our intensive care units (ICU) after hepato-biliary pancreatic surgery. Continuous blood glucose measurement was performed from the beginning of the operation to ICU discharge using the intravenous continuous monitor STG-55 (Nikkiso, Tokyo, Japan) and the subcutaneous continuous monitor iPro2 (Medtronic Japan, Tokyo, Japan). The STG-55 measured the glucose level in real time, and the iPro2 measured this every 5 min. We compared glucose levels obtained using the two devices every 5 min using a Bland–Altman plot and a regression analyses. A total of 3592 comparative samples in 15 cases were analyzed. The mean glucose level measured using the STG-55 was 139 ± 21 mg/dl, and that measured using the iPro2 was 144 ± 31 mg/dl. A linear regression line had the equation of the formy= 0.225x+ 106. The coefficient of determination was 0.11, and theF-test significance level was set asp< 0.01. The mean of the differences was −5.2 mg/dl, with a 95 % agreement limit of −67 to + 57 mg/dL. The percent error was 44 %. In conclusion, the current study suggests that subcutaneous and intravenous continuous glucose monitoring was not highly correlated during either surgery or ICU stay.