Early destructive effect of sunlight on human skin.
Early destructive effect of sunlight on human skin.
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阳光对人体皮肤的早期破坏作用。
DOI：
10.1001/jama.1969.03160390039008
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发表时间：
1969
期刊：
影响因子：
--
通讯作者：
A. Kligman
中科院分区：
文献类型：
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作者：
A. Kligman
白色人的面部皮肤在整个人类寿命期间被评估为弹性纤维变化的严重程度，作为日光损伤的指标。弹性增生早在第一个十年就开始了，并且在30岁之前的大多数年轻人中明显可见。在40岁以后，大多数人都有严重的弹性组织异常，最终导致大规模变性。在损伤的广泛性在临床上可见之前，弹性组织变性的变化已经相当晚期了。未暴露的皮肤中的弹性纤维在老年时仅略有增加。面部不同区域的弹性组织损伤程度与这些区域接受的阳光量有关，耳缘和脸颊最大，下巴和眉毛下最小。阳光，而不是先天衰老，是导致衰老皮肤最严重表现的主要原因。
The facial skin of white persons has been assessed throughout the human life span for the severity of elasticfiber changes as an indicator of sunlight damage. Elastic hyperplasia began as early as the first decade and was clearly evident in a majority of young adults before the age of 30. Beyond the fourth decade most persons had serious elastic-tissue abnormalities culminating in massive degeneration. The elastotic changes were quite advanced before the extensiveness of the damage became visible clinically. The unexposed skin of the buttock exhibited only a slight increase in elastic fibers in old age. The degree of elastic-tissue damage in different regions of the face was in relation to the amount of sunlight these received, greatest on the ear rim and cheek, least under the chin and eyebrows. Sunlight, not innate aging, is mainly responsible for the worst manifestation of senile skin.