Effectiveness of Prism Adaptation in Neglect Rehabilitation A Controlled Trial Study
Effectiveness of Prism Adaptation in Neglect Rehabilitation A Controlled Trial Study
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DOI：
10.1161/strokeaha.108.530485
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发表时间：
2009-04-01
期刊：
影响因子：
8.3
通讯作者：
Ladavas, Elisabetta
中科院分区：
文献类型：
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作者：
Serino, Andrea;Barbiani, Moreno;Ladavas, Elisabetta
背景和目的：本研究旨在探讨基于棱镜适应（PA）的2周治疗对忽视恢复的有效性，并与无棱镜的类似视觉运动训练（即中性指向（NP））进行比较。方法：将20例被忽视患者分为两组，一组接受PA治疗（PA组），另一组接受NP治疗（NP组），每天10次，为期2周。NP治疗结束后，NP组患者同时进行PA治疗。在每次治疗前后和PA治疗结束后1个月评估忽视。结果：PA和NP治疗后大鼠视觉空间能力均有改善；然而，PA组患者的改善明显高于NP组患者。此外，NP组患者在接受PA治疗后，进一步提高到PA组患者的水平，即达到非病理评分。治疗结束后1个月证实了PA的持久有益效果。结论：虽然基于指向的视觉运动训练可能会部分改善忽视症状，但PA诱导的感觉运动参考系向左重新校准对获得适当的忽视恢复是有效的。(中风。2009;40:1392 - 1398)。
Background and Purpose-This study was conducted to investigate the effectiveness on neglect recovery of a 2-week treatment based on prism adaptation (PA) in comparison to an analogous visuomotor training performed without prisms, ie, neutral pointing (NP).Methods-Twenty neglect patients were divided into 2 matched groups, one was submitted to PA (PA group) and the other to NP (NP group) for 10 daily sessions over a period of 2 weeks. After the end of NP treatment, the patients in the NP group were also submitted to PA treatment. Neglect was assessed before and after each treatment and I month after the end of the PA treatment.Results-Visuospatial abilities improved after both PA and NP treatment; however, the improvement was significantly higher in the patients in the PA group than in the patients in the NP group. Moreover, when the patients in the NP group were submitted to PA, they further improved up to the level reached by patients in the PA group, ie, to nonpathological scores. Long-lasting beneficial effects of PA were confirmed I month from the end of treatment.Conclusion-The leftward recalibration of sensorimotor reference frames induced by PA is effective to obtain proper neglect recovery, although visuomotor training based on pointing might partially improve neglect symptoms. (Stroke. 2009;40:1392-1398.)