DOES MATERNAL TOBACCO SMOKING MODIFY THE EFFECT OF ALCOHOL ON FETAL GROWTH
DOES MATERNAL TOBACCO SMOKING MODIFY THE EFFECT OF ALCOHOL ON FETAL GROWTH
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DOI：
10.2105/ajph.81.1.69
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发表时间：
1991-01-01
影响因子：
12.7
通讯作者：
OLSEN, SF
中科院分区：
文献类型：
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作者：
OLSEN, J;PEREIRA, AD;OLSEN, SF
丹麦两个城市1984-87年的11698名孕妇在怀孕36周时通过自填式问卷记录了吸烟和饮酒习惯，占所有此类女性的80%以上。每周饮酒120克或更多与吸烟者婴儿平均出生体重的下降幅度大于非吸烟者(非吸烟者约40克，吸烟者约200克)有关。考虑到吸烟者的平均出生体重低于不吸烟者，这一点尤其令人震惊。研究发现，母亲既不吸烟也不喝酒的婴儿与吸烟酗酒母亲的婴儿出生体重相差超过500克。我们的数据表明，在给孕妇关于饮酒的建议时，应该考虑到女性的吸烟习惯。
Smoking and drinking habits were registered by a self-administered questionnaire in 36th week of gestation in 11,698 pregnant women, more than 80 percent of all such women in two Danish cities 1984-87. Alcohol consumption of 120 g/week or more was associated with a greater reduction in the average birthweight in the babies of smokers than of non-smokers (about 40 grams for the non-smokers and about 200 grams for the smokers). This is particularly striking considering that the average birthweight for smokers is lower than for non-smokers. A birthweight difference of more than 500 grams was found between babies of mothers who neither smoked nor drank and mothers who smoke and drank heavily. Our data suggest that women's smoking habits should be taken into consideration when giving pregnant women advice about drinking.