Three-dimensional array-based group testing algorithms.

Three-dimensional array-based group testing algorithms.
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DOI:
10.1111/j.1541-0420.2008.01158.x
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发表时间:
2009-09
期刊:
影响因子:
1.9
通讯作者:
Hudgens MG
Hudgens MG
中科院分区:
数学3区
文献类型:
--
作者:
Kim HY;Hudgens MG

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我们推导出的三维阵列为基础的测试算法的情况下,存在测试错误识别的操作特性。所研究的操作特性包括效率(即,每个样本的预期测试次数)和错误率(例如,灵敏度、特异性、阳性和阴性预测值)。通过比较所提出的算法与以前研究的层次和二维阵列算法检测最近在北卡罗来纳州的HIV感染的方法进行说明。我们的研究结果表明,三维阵列为基础的算法可以更有效,更准确地比以前提出的算法在设置测试错误和低患病率。
We derive the operating characteristics of three-dimensional array-based testing algorithms for case identification in the presence of testing error. The operating characteristics investigated include efficiency (i.e., expected number of tests per specimen) and error rates (e.g., sensitivity, specificity, positive, and negative predictive values). The methods are illustrated by comparing the proposed algorithms with previously studied hierarchical and two-dimensional array algorithms for detecting recent HIV infections in North Carolina. Our results indicate that three-dimensional array-based algorithms can be more efficient and accurate than previously proposed algorithms in settings with test error and low prevalence.
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