Dual Catalytic Strategy for Forging sp2-sp3 and sp3-sp3 Architectures via β-Scission of Aliphatic Alcohol Derivatives
Dual Catalytic Strategy for Forging sp2-sp3 and sp3-sp3 Architectures via β-Scission of Aliphatic Alcohol Derivatives
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DOI：
10.1021/jacs.0c11172
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发表时间：
2020-12-09
影响因子：
15
通讯作者：
Martin, Ruben
中科院分区：
文献类型：
--
作者：
Cong, Fei;Lv, Xin-Yang;Martin, Ruben
公开了一种通过脂肪醇衍生物与芳基和烷基卤化物的催化β-断裂来构建sp(2)-sp(3)和sp(3)-sp(3)碳键的双平台。该方案的特点是底物适用范围广且适用性强，即使在后期官能化的情况下也是如此。
A dual platform for forging sp(2)-sp(3) and sp(3)-sp(3) carbon bonds via catalytic beta-scission of aliphatic alcohol derivatives with both aryl and alkyl halides is disclosed. This protocol is distinguished by its wide substrate scope and broad applicability, even in the context of late-stage functionalization.