Different roles for androgens and estrogens in the susceptibility to autoimmune rheumatic diseases
Different roles for androgens and estrogens in the susceptibility to autoimmune rheumatic diseases
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DOI：
10.1016/s0889-857x(05)70171-x
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发表时间：
2000-11-01
影响因子：
2.3
通讯作者：
Wilder, RL
中科院分区：
文献类型：
--
作者：
Cutolo, M;Wilder, RL
雄激素和雌激素调节自身免疫性风湿病的易感性和进展。在任何浓度下，雄激素似乎主要抑制细胞和体液免疫，而在生理浓度下，雌激素似乎增强体液免疫并降低细胞免疫。
Androgens and estrogens modulate susceptibility and progression to autoimmune rheumatic disease. At any concentration, androgens seem to be primarily suppressive on cellular and humoral immunity whereas at physiologic concentrations, estrogens seem to enhance humoral immunity and decrease cellular immunity.