Genotypic Intratumoral Heterogeneity in Breast Carcinoma With HER2/neu Amplification
Genotypic Intratumoral Heterogeneity in Breast Carcinoma With HER2/neu Amplification
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DOI：
10.1309/ajcp09vutzwzxbmj
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发表时间：
2009-05-01
影响因子：
3.5
通讯作者：
Bonetti, Franco
中科院分区：
文献类型：
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作者：
Brunelli, Matteo;Manfrin, Erminia;Bonetti, Franco
我们评估了30例HER 2/neu扩增的乳腺导管癌的瘤内异质性，根据美国临床肿瘤学会/美国病理学家学会（ASCO/CAP）标准评分，免疫表达为3+。高级别扩增（比率>= 4.0）与低级别扩增（比率>2.2，
We evaluated intratumoral heterogeneity of 30 ductal breast carcinomas with HER2/neu amplification, scored by the American Society of Clinical Oncology/College of American Pathologists (ASCO/CAP) criteria, and 3+ immunoexpression. High-grade (ratio >= 4.0) vs low-grade amplification (ratio >2.2 to