Plasma free reversible and irreversible microfluidic bonding.

Plasma free reversible and irreversible microfluidic bonding.
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无等离子体可逆和不可逆微流体键合。

DOI:
10.1039/c6lc01338d
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发表时间:
2017
期刊:
影响因子:
6.1
通讯作者:
Khine,M
Khine,M
中科院分区:
工程技术1区
文献类型:
--
作者:
Chu,M;Nguyen,TT;Lee,EK;Morival,JL;Khine,M

文献摘要

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我们展示了一种简便的无等离子体工艺,可使用基于 PDMS 的粘合剂聚合物混合物制造可逆和不可逆密封的微流控芯片。这是一种与当前 PDMS 微流体工艺兼容的通用方法。它可以更轻松地制造多层微流体装置,并且与细胞培养的蛋白质微图案兼容。与我们的 Shrinky-Dink 微流控原型技术相结合,无需任何固定设备即可完成完整的微流控器件制造,从而使微流控技术走进课堂。
We demonstrate a facile, plasma free process to fabricate both reversibly and irreversibly sealed microfluidic chips using a PDMS-based adhesive polymer mixture. This is a versatile method that is compatible with current PDMS microfluidics processes. It allows for easier fabrication of multilayer microfluidic devices and is compatible with micropatterning of proteins for cell culturing. When combined with our Shrinky-Dink microfluidic prototyping, complete microfluidic device fabrication can be performed without the need for any capital equipment, making microfluidics accessible to the classroom.