Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging.
Folic acid-functionalized fluorescent gold nanoclusters with polymers as linkers for cancer cell imaging.
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DOI：
10.1039/c3cc44256j
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发表时间：
2013-08
影响因子：
4.9
通讯作者：
J. Qiao;Xiaoyu Mu;L. Qi;Jingjing Deng;L. Mao
中科院分区：
文献类型：
--
作者：
J. Qiao;Xiaoyu Mu;L. Qi;Jingjing Deng;L. Mao
研究了一种新型的纳米缀合物，其含有由卵清蛋白作为荧光部分保护的超小的水溶性AuNCs，叶酸作为靶向配体和均聚物N-丙烯酰氧基琥珀酰亚胺作为连接体。此外，已经证明了纳米缀合物对HeLa细胞的特异性染色。
A novel nano-conjugate containing ultrasmall water-soluble AuNCs protected by ovalbumin as the fluorescent part, folic acid as the targeting ligand and a homopolymer N-acryloxysuccinimide as the linker has been investigated. Moreover, specific staining of HeLa cells by the nano-conjugate has been demonstrated.