A case of familial Michelin tire baby syndrome.
A case of familial Michelin tire baby syndrome.
复制标题
家族性米其林轮胎婴儿综合症一例。
DOI：
10.1111/1346-8138.12826
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发表时间：
2015
期刊：
影响因子：
3.1
通讯作者：
Ishikawa O.
中科院分区：
文献类型：
--
作者：
Kato M;Shimizu A;Ishikawa O.
图1.(a)外阴大阴唇上聚集的多个肤色丘疹。(b)手掌上的角化性丘疹和凹坑。(c)右手掌皮损的临床特写。(d)脚底的角化性丘疹和凹坑临床特写。(e)右脚底皮损的临床特写。(f)大阴唇丘疹的组织病理学显示轻度角化过度，不规则棘层肥厚和基底上裂。(g) 较高放大倍数显示明显的基底上裂和表皮内棘层松解症，伴有轻微角化不良。(h) 手掌病变的组织病理学显示角化过度和局灶性棘层松解伴基底上裂。(i) 较高放大倍数显示基底上裂和角化不良，伴有圆形和颗粒状角化不良（苏木精-伊红，原始放大倍数：9 [f, h] 9100；[g, i] 9400）。
Figure 1.(a) Multiple skin-colored papules grouped on the labia majora of the vulva.(b) Keratotic papules and pits on the palms.(c) Clinical close-up of the lesions on the right palm.(d) Keratotic papules and pits on the soles.(e) Clinical close-up of the lesions on the right sole.(f) Histopathology of a papule on the labia majora shows mild hyperkeratosis, irregular acanthosis and suprabasal clefting.(g) Higher magnification reveals prominent suprabasal clefts, and intraepidermal acantholysis with minimal dyskeratosis.(h) Histopathology of a lesion on the palm shows hyperkeratosis and focal acantholysis with suprabasal clefts.(i) Higher magnification reveals suprabasal clefts and dyskeratosis with corps ronds and grains (hematoxylin–eosin, original magnifications: 9 [f, h] 9100;[g, i] 9400).