An unusual presentation of immotile-cilia syndrome with azoospermia: Case report and literature review.
An unusual presentation of immotile-cilia syndrome with azoospermia: Case report and literature review.
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DOI：
10.4103/0970-2113.56352
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发表时间：
2009-10
期刊：
影响因子：
--
通讯作者：
Shah KV
中科院分区：
文献类型：
--
作者：
Dixit R;Dixit K;Jindal S;Shah KV
不动纤毛综合征是一种罕见的疾病，其特征是慢性复发性鼻窦-肺感染，气管支气管清除功能受损，约50%的病例出现异位，精液分析中存在形态正常的活精子但不动精子。在这份报告中，我们描述了一个不寻常的介绍不动纤毛综合征无精子症的32岁男性患者。诊断基于反复呼吸道感染、支气管扩张、上颌窦炎、额窦发育不全、贲门反位、鼻粘膜纤毛清除功能受损等病史。精液分析显示无精子症，无任何证据表明附睾或输精管阻塞。睾丸活检可见正常精子发生。
Immotile-cilia syndrome is a rare disorder characterized by chronic recurrent sino-pulmonary infection, impaired tracheobronchial clearance, situs inversus in about 50% of cases, and living but immotile spermatozoa of normal morphology in semen analysis. In this report, we describe an unusual presentation of immotile-cilia syndrome with azoospermia in a 32-year-old male patient. The diagnosis was based on history of recurrent respiratory tract infection, bronchiectasis, maxillary sinusitis, hypoplasia of frontal sinuses, dextrocardia with situs inversus, impaired nasal mucociliary clearance, etc. Semen analysis revealed azoospermia without any evidence of obstruction in epididymides or vas deference. Normal spermatogenesis was seen on testicular biopsy.