Ultrastructural effects of the Bacillus sphaericus mosquito larvicidal toxin on cultured mosquito cells.

Ultrastructural effects of the Bacillus sphaericus mosquito larvicidal toxin on cultured mosquito cells.
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球形芽孢杆菌杀幼虫毒素对培养的蚊子细胞的超微结构影响。

DOI:
10.1016/0022-2011(87)90085-1
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发表时间:
1987
影响因子:
3.4
通讯作者:
Titus,M
Titus,M
中科院分区:
生物学3区
文献类型:
--
作者:
Davidson,EW;Titus,M

文献摘要

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球形芽孢杆菌粗提物及其纯化毒素引起致倦库蚊细胞线粒体嵴、内质网和高尔基体分泌囊泡的扩张和浓缩。随着中毒的进展,细胞膜逐渐失去完整性。这些观察结果进行了比较,超微结构的病理由于苏云金芽孢杆菌培养细胞和幼虫,并讨论了有关的约束力和内化的毒素。
CrudeBacillus sphaericusextracts and purified toxin derived from these extracts caused very rapid changes in culturedCulex quinquefasciatuscells, including dilation of mitochondrial cristae, endoplasmic reticula, and Golgi secretory vesicles, and condensation of the mitochondria. The cell membrane gradually lost integrity as intoxication progressed. These observations are compared to the ultrastructure of the pathology due toBacillus thuringiensisin cultured cells and larvae, and are discussed in relation to binding and internalization of the toxin.