Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.
Isolation of bisindole alkaloids that inhibit the cell cycle from Myxomycetes Arcyria ferruginea and Tubifera casparyi.
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DOI：
10.1016/s0960-894x(03)00592-4
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发表时间：
2003-09
影响因子：
2.7
通讯作者：
Satomi Nakatani;Ayano Naoe;Yukinori Yamamoto;T. Yamauchi;N. Yamaguchi;M. Ishibashi
中科院分区：
文献类型：
--
作者：
Satomi Nakatani;Ayano Naoe;Yukinori Yamamoto;T. Yamauchi;N. Yamaguchi;M. Ishibashi
从粘菌 Arcyria ferruginea 中，已分离出一种新的双吲哚生物碱二氢arcyriarubin C (1) 以及两种已知的双吲哚，即arcyriarubin C (2) 和arcyriaflavin C (3)，并且还从Tubifera casparyi 中分离出arcyriaflavin C (3) 和arcyriaflavin B (4)。 Arcyriaflavin C (3) 分别在 10 ng/mL 和 100 ng/mL 时在 G1 和 G2/M 阶段表现出细胞周期抑制作用。
From a myxomycete Arcyria ferruginea, dihydroarcyriarubin C (1), a new bisindole alkaloid, has been isolated together with two known bisindoles, arcyriarubin C (2) and arcyriaflavin C (3), and arcyriaflavin C (3) was also isolated from Tubifera casparyi together with arcyriaflavin B (4). Arcyriaflavin C (3) exhibited cell cycle inhibition effect at G1 and G2/M stage at 10 and 100ng/mL, respectively.