Assessment of left ventricular function by indices derived from aortic flow velocity.
Assessment of left ventricular function by indices derived from aortic flow velocity.
复制标题
通过主动脉血流速度指数评估左心室功能。
DOI：
10.1136/hrt.38.1.18
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发表时间：
1976
影响因子：
--
通讯作者：
M. Webb
中科院分区：
文献类型：
--
作者：
M. Kolettis;B. S. Jenkins;M. Webb
本文应用导管流速探头对40例常规诊断性心导管检查患者的主动脉血流速度和加速度进行了测量。十个不同的变量来自主动脉瓣速度测量，并测试其区分左心室（LV）功能好坏的能力。根据压力、平均流量和定量电影血管造影的8项常规左室功能指标，将患者分为3组：1组，左室功能良好; 2组，左室功能中等; 3组，左室功能差。主动脉峰值速度和最大加速度与每搏输出量相关性良好，因此是LV泵功能的指标。主动脉峰值流速与左室每搏功也有显著相关性。主动脉峰值速度和最大加速度不能区分三组患者，与常规左室功能指标相关性差。每搏输出量的平均值在组1和组2之间以及组1和组3之间存在显著差异，并且与常规功能指数的相关性更好。用每搏输出量除以最大加速度可以最好地区分左室功能正常和异常，但用每搏输出量除以峰值速度比单独区分每搏输出量更好。每搏输出量除以最大加速度也给出了更显着的个人相关性与传统的功能指数比任何其他变量来自主动脉瓣速度。
The velocity and acceleration of aortic blood flow were measured by means of a catheter velocity probe in 40 patients during routine diagnostic cardiac catheterization. Ten different variables were derived from the aortic velocity measurements, and their ability to discriminate between good and bad left ventricular (LV) function was tested. By means of eight conventional indices of LV function derived from pressure, mean flow, and quantitative cineangiography, the patients were divided into 3 groups: group 1, good LV function; group 2, moderate LV function; group 3, poor LV function. Aortic peak velocity and maximal acceleration correlated well with stroke volume and were thus indices of LV pump function. Aortic peak velocity also showed a significant correlation with LV stroke work. Both aortic peak velocity and maximal acceleration failed to discriminate between the three groups of patients, and correlated poorly with conventional indices of LV function. The mean values of stroke volume differed significantly between groups 1 and 2, and between groups 1 and 3, and also correlated better with the conventional functional indices. The best discrimination between normal and abnormal LV function was provided by dividing stroke volume by maximal acceleration, but stroke volume divided by peak velocity discriminated better than stroke volume alone. Stroke volume divided by maximal acceleration also gave more significant individual correlations with the conventional functional indices than did any other variable derived from aortic velocity.