An electron microscopical approach to efficacy screening of physical sunscreens
An electron microscopical approach to efficacy screening of physical sunscreens
复制标题
电子显微镜方法筛选物理防晒霜的功效
DOI：
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
E. Gooris
中科院分区：
文献类型：
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作者：
J. Hemmerlé;P. Msika;E. Gooris
本研究的目的是彻底调查超细二氧化钛晶体的空间分布在不同的物理防晒配方，以及他们的应用到人体皮肤上。测试的防晒产品，实现了两个选定的市售的矿物阻断剂（TiO 2）在两种类型的配方。由于氧化物颗粒的微小尺寸，评估主要在扫描和透射电子显微镜下进行。物理防晒霜的有效性直接与矿物成分对角质层的规则和均匀涂层有关。因此，我们系统地分析了TiO2在不同乳霜中的分散体的微观结构。最重要的是，我们将注意力集中在局部应用于皮肤后的二氧化钛存款上。暴露结果强调了正确选择原材料的重要性，并证明了化妆品载体所起的作用。
The aim of this study was to thoroughly investigate the spatial distribution of ultrafine titanium dioxide crystals in different physical sunscreen formulas as well as after their application onto human skin. The tested sun care products were realized by incorporation of two selected commercially available mineral blocking agents (TiO 2 ) in two types of formulations. Due to the minute sizes of the oxide particles, the assessments were mainly carried out in scanning and transmission electron microscopy. Effectiveness of a physical sunscreen is directly related to the regular and uniform coating of the stratum corneum with the mineral ingredient. Therefore, we systematically analyzed the microstructure of the TiO 2 dispersion in the different creams. Above all, we focused our attention to the titanium dioxide deposit after topical applications to the skin. The exposed results emphasize the importance of a proper selection of the raw material and demonstrate the role played by the cosmetic vehicle.
DOI：
10.1002/jbm.820290111
发表时间：
1995-01-01
期刊：
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH
影响因子：
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作者：
EFFAH, EAB;BIANCO, PD;DUCHEYNE, P
通讯作者：
DUCHEYNE, P
影响因子：
7.7
作者：
COTHREN, RM;RICHARDSKORTUM, R;PETRAS, RE
通讯作者：
PETRAS, RE