Comparison of expert graders to computer-assisted image analysis of the retina in retinopathy of prematurity

Comparison of expert graders to computer-assisted image analysis of the retina in retinopathy of prematurity
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早产儿视网膜病变专家分级员与计算机辅助视网膜图像分析的比较

DOI:
10.1136/bjo.2010.185363
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发表时间:
2011
影响因子:
4.1
通讯作者:
G. Quinn
G. Quinn
中科院分区:
医学2区
文献类型:
--
作者:
Deepika N. Shah;Clare M. Wilson;G. Ying;K. Karp;K. Cocker;Jeffrey Ng;E. Schulenburg;A. Fielder;M. Mills;G. Quinn

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目的确定早产儿视网膜病变患者窄视野图像中视网膜宽度和迂曲度与专家分级和计算机辅助图像分析之间的相关性。方法根据早产儿视网膜病变(ROP)的严重程度选择11例数字图像。使用计算机辅助视网膜图像分析(CAIAR)(一种图像分析软件)并由4名ROP专家分析窄视野图像的血管宽度和迂曲度。斯皮尔曼相关系数(ρ)评估CAIAR评分与专家评分的相关性。班级内的相关性评估评分员之间的协议。使用方差分析和广义估计方程比较ROP严重程度和治疗状态之间的宽度和迂曲度。结果专家测量值与CAIAR测量值在小静脉宽度(ρ=0.57-0.66)和小动脉迂曲度(ρ=0.71-0.81)方面具有良好的相关性。四个年级学生的测量结果一致(小静脉宽度和小动脉迂曲度的类内相关系数分别为0.49和0.69)。ROP的严重程度增加(无预加/加,预加,加)与较大的宽度(两个分级者中线性趋势p=0.02)和迂曲度(所有分级者中线性趋势p<0.03)相关。治疗眼和未治疗眼之间通过CAIAR和分级仪进行的迂曲度测量存在统计学差异(p<0.002)。结论:我们发现专家评分者对血管迂曲度和宽度的评估与使用窄视野图像的CAIAR之间存在中度相关性。
Aims To determine correlation of width and tortuosity between expert graders and computer-assisted image analysis of the retina in narrow-field images of eyes with retinopathy of prematurity. Methods 11 digital images were selected based on severity of retinopathy of prematurity (ROP). Narrow field images were analysed for width and tortuosity of vessels using computer-aided image analysis of the retina (CAIAR), an image analysis software, and by four ROP experts. Spearman correlation coefficients (ρ) assessed the correlation of CAIAR grading with expert grading. Intra-class correlations assessed agreement among graders. Width and tortuosity were compared among severity of ROP and treatment status using analysis of variance and generalised estimating equations. Results Expert measurements correlated well with measures from CAIAR for venule width (ρ=0.57–0.66) and arteriole tortuosity (ρ=0.71–0.81). Measurements from four graders agreed moderately well (intra-class correlations were 0.49 and 0.69 for venule width and arteriole tortuosity, respectively). Increased severity of ROP (no pre-plus/plus, pre-plus, plus) was associated with larger width (linear trend p=0.02 in two graders) and tortuosity (linear trend p<0.03 in all graders). Tortuosity measurements by CAIAR and graders were statistically different between treated and untreated eyes (p<0.002). Conclusions We found moderate correlation between expert graders' assessment of vessel tortuosity and width and CAIAR using narrow-field images.
早产儿视网膜病变阈值后 15 年的结果:早产儿视网膜病变冷冻疗法多中心试验的最终结果。
DOI: 10.1001/archopht.123.3.311
发表时间: 2005
期刊: Archives of ophthalmology (Chicago, Ill. : 1960)
影响因子: --
作者:
Palmer,EarlA;Hardy,RobertJ;Dobson,Velma;Phelps,DaleL;Quinn,GrahamE;Summers,CGail;Krom,CarolP;Tung,Betty;CryotherapyforRetinopathyofPrematurityCooperativeGroup
通讯作者: CryotherapyforRetinopathyofPrematurityCooperativeGroup
DOI: 10.1001/archopht.120.11.1470
发表时间: 2002-11-01
影响因子: --
作者:
Reynolds, JD;Dobson, V;Tung, B
通讯作者: Tung, B