Absolute Ethanol Embolization of Infiltrating-diffuse Extracranial Arteriovenous Malformations in the Head and Neck
Absolute Ethanol Embolization of Infiltrating-diffuse Extracranial Arteriovenous Malformations in the Head and Neck
复制标题
无水乙醇栓塞治疗头颈部弥漫性颅外动静脉畸形
DOI：
10.1016/j.ejvs.2015.02.020
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发表时间：
2015-07-01
影响因子：
5.7
通讯作者：
Fan, X.
中科院分区：
文献类型：
--
作者：
Su, L.;Wang, D.;Fan, X.
目的：头颈部浸润型颅外动静脉畸形（AVM）可引起美容、功能和心理问题。本研究报告了一项单中心经验，并评估了单独使用无水乙醇栓塞治疗头颈部浸润性颅外AVM的临床安全性和有效性。方法：从2011年6月至2013年6月，168名患有头颈部颅外AVM的连续患者接受了分期乙醇或其他栓塞方法，其中66例患者在头部和颈部患有III型浸润-弥漫性颅外AVM。仅使用了无水乙醇栓塞，并进行了回顾性评价。所有患者均在临床随访时进行评估（平均16.8个月;范围12-38个月）。通过评估症状和体征的临床结果，以及通过随访angiography.Results的断流程度确定治疗结果：对于96个会议，在一个单一的栓塞会话中使用的乙醇的平均量为13.6 mL，范围是从2到25 mL。66例患者中五十六例有效控制，AVM 100%断流，其余10例患者部分缓解，AVM不同程度断流（50-99%）。在96例手术中的16例中，66例患者中有5例发生一过性血红蛋白尿。无严重并发症。结论：单独使用乙醇栓塞治疗似乎是有效和安全的浸润性弥漫性颅外AVM在头部和颈部的管理。(C)2015年欧洲血管外科学会。由爱思唯尔有限公司出版。保留所有权利。
Objective: Extracranial arteriovenous malformations (AVMs) of an infiltrative type in the head and neck can cause cosmetic, functional, and, psychological problems. This study reports a single center experience and evaluates the clinical safety and effectiveness of the sole use of absolute ethanol embolotherapy for infiltrative extracranial AVMs in the head and neck.Method: From June 2011 to June 2013, 168 consecutive patients with extracranial AVMs in the head and neck underwent staged ethanol or other methods of embolization, of whom 66 patients had infiltrating-diffuse extracranial AVMs of type Ill in the head and neck. Absolute ethanol embolization was solely used and retrospectively evaluated. All patients were assessed at clinical follow up (mean 16.8 months; range 12-38 months). Therapeutic outcomes were determined by evaluating the clinical outcome of symptoms and signs, as well as the degree of devascularization by follow up angiography.Results: For the 96 sessions, the mean amount of ethanol used in a single embolization session was 13.6 mL and range was from 2 to 25 mL. Fifty-six of the 66 patients were effectively controlled with 100% of the AVMs devascularized, and the remaining 10 patients had partial remission with various degrees of AVM devascularization (50-99%). Transient hemoglobinuria occurred in five of the 66 patients for a total 16 out of 96 procedures. There were no major complications.Conclusions: The sole use of ethanol ennbolotherapy appears to be efficacious and safe in the management of infiltrating-diffuse extracranial AVMs in the head and neck. (C) 2015 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.