Effects of Water-soluble Components of Cheese on Experimental Caries in Humans
Effects of Water-soluble Components of Cheese on Experimental Caries in Humans
复制标题
奶酪水溶性成分对人类实验性龋齿的影响
DOI：
10.1177/00220345870660010801
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发表时间：
1987
影响因子：
7.6
通讯作者：
G. Jenkins
中科院分区：
文献类型：
--
作者：
M.F. de A. Silva;R. Burgess;H. Sandham;G. Jenkins
采用7天口内致龋试验（ICT），观察了陈年切达干酪水溶性成分对实验性龋的影响。将两个牛牙釉质块放置在五名志愿者的牙齿矫正器的每个颊侧凸缘中。将每个器具的一侧（实验）浸入奶酪的25%水提取物中5分钟，而另一侧（对照）浸入去离子水中。此后，立即将器具放回受试者的口腔中，并用10%蔗糖进行两次60秒的冲洗。这些程序每天重复六次。通过牙釉质显微硬度评估，奶酪提取物蘸料使蔗糖的致龋性平均降低55.7%（p<0.01）。无论是平均静息pH值，也不是平均最低pH值响应蔗糖之间的实验和对照侧显着不同。实验侧牙菌斑钙浓度（32.44 μg/mg）明显高于对照侧（19.36 μg/mg）（P<0.01）。实验侧菌斑磷浓度（12.90 μg/mg）高于对照侧（9.61 μg/mg），但差异无统计学意义。这些结果表明，奶酪具有一种或多种水溶性组分，可减少人类受试者的实验性龋齿。
The effect of water-soluble components of extra-old Cheddar cheese on experimental caries was tested by means of the seven-day intraoral cariogenicity test (ICT). Two bovine enamel blocks were placed in each buccal flange of the dental appliances of five volunteers. One side of each appliance (experimental) was dipped in a 25% water extract of the cheese for five min, while the other side (control) was dipped in de-ionized water. Immediately thereafter, the appliance was returned to the subject's mouth, and two 60-second rinses with 10% sucrose were performed. These procedures were repeated six times per day. The cheese-extract dippings reduced the cariogenicity of the sucrose by an average of 55.7% (p<0.01), as assessed by enamel microhardness. Neither the mean resting pH nor the mean minimum pH in response to sucrose was significantly different between the experimental and control sides. The concentration of calcium was significantly higher in plaque from the experimental side (32.44 μg/mg) as compared with the control side (19.36 μg/mg, p<0.01). The concentration of plaque phosphorus was higher on the experimental side (12.90 μg/mg) than on the control side (9.61 μg/mg); however, the difference was not statistically significant. These results show that cheese has one or more water-soluble components which reduce experimental caries in human subjects.