The B144-H-2Db interval and the location of a mouse homologue of the human D6S81E locus.
The B144-H-2Db interval and the location of a mouse homologue of the human D6S81E locus.
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B144-H-2Db 间隔和人类 D6S81E 基因座的小鼠同源物的位置。
DOI：
10.1007/bf02114974
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发表时间：
1990
期刊：
影响因子：
3.2
通讯作者：
Nakamura,I
中科院分区：
文献类型：
--
作者：
Wroblewski,JM;Kaminsky,SG;Milisauskas,VK;Pittman,AM;Chaplin,DD;Spies,T;Nakamura,I
利用来自C57 BL/SnCr小鼠的基因组DNA的pWE 14粘粒文库，进行从B144-Tnf基因簇到H-2Db基因的基因组步移。B144与H-2D之间的距离为80 kb。Db单倍型的这一区域在长度和酶切位点分布上与相应的Dd区域相似。人D 6S 81 E基因座的小鼠同源物位于Db端粒的10 kb处。
A genomic walk was carried out from theB144-Tnfgene cluster to theH-2Dbgene, using a pWE14 cosmid library of genomic DNA from a C57BL/SnCr mouse. The distance betweenB144andH-2Dwas 80 kb. This region of theDbhaplotype was similar to the correspondingDdregion in length and restriction site distribution. A mouse homologue of the humanD6S81Elocus was found 10 kb telomeric toDb.