Controlled Synthesis of 3D Multi-Compartmental Particles with Centrifuge-Based Microdroplet Formation from a Multi-Barrelled Capillary
Controlled Synthesis of 3D Multi-Compartmental Particles with Centrifuge-Based Microdroplet Formation from a Multi-Barrelled Capillary
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DOI：
10.1002/adma.201102560
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发表时间：
2012-03-08
影响因子：
29.4
通讯作者：
Takeuchi, Shoji
中科院分区：
文献类型：
--
作者：
Maeda, Kazuki;Onoe, Hiroaki;Takeuchi, Shoji
据报道，使用离心液滴喷射装置（CDSD）控制合成微型多室颗粒。将海藻酸钠溶液引入多筒毛细管中，在超高重力下在毛细管孔口形成液滴，并在 CaCl2 溶液中凝胶化。颗粒的大小、形状和分隔是受控的。证明了 Jurkat 细胞和磁性胶体共同封装到 Janus 颗粒中。颗粒对磁场表现出敏感反应，而封装细胞的存活率为91%。Janus
Controlled synthesis of micro multi-compartmental particles using a centrifuge droplet shooting device (CDSD) is reported. Sodium alginate solutions introduced in a multi- barreled capillary form droplets at the capillary orifice under ultrahigh gravity and gelify in a CaCl2 solution. The size, shape, and compartmentalization of the particles are controlled. Co-encapsulation of Jurkat cells and magnetic colloids into Janus particles is demonstrated. The particles present sensitive reaction toward magnetic fields, while the viability of the encapsulated cells is 91%.Janus