Atrioventricular Block Precipitated by Isoproterenol

Atrioventricular Block Precipitated by Isoproterenol
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DOI:
10.1111/anec.12192
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发表时间:
2015-07-01
影响因子:
1.9
通讯作者:
Stroobandt, Roland X.
Stroobandt, Roland X.
中科院分区:
医学4区
文献类型:
--
作者:
Barold, S. Serge;De Wilde, Hans E.;Stroobandt, Roland X.

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1例有近晕厥、左束分支传导阻滞和无记录房室(AV)传导阻滞病史的患者在电生理学研究(EPS)期间接受异丙肾上腺素输注。异丙肾上腺素诱发典型的2:1希氏房室传导阻滞,最可能发生在记录希氏-浦肯野电位的部位近端,与右束分支活动一致。阵发性房室传导阻滞也发生在异丙肾上腺素洗脱期间,位于假定右束分支电位远端的不同部位。异丙肾上腺素可能是有价值的诊断,偶尔病人怀疑房室传导阻滞,其中的EPS是unrevealing和药物挑战是阴性的。
An isoproterenol infusion was administered during an electrophysiologic study (EPS) in a patient with a history of near syncope, left bundle branch block, and no documented atrioventricular (AV) block. Isoproterenol precipitated classic 2:1 Infra-Hisian AV block most probably proximal to the site of recording a His-Purkinje potential consistent with right bundle branch activity. Paroxysmal AV block also occurred during isoproterenol washout at a different site located distal to the presumed right bundle branch potential. Isoproterenol may be valuable diagnostically in an occasional patient suspected of AV block in whom an EPS is unrevealing and a drug challenge is negative.