Tanay virus, a new species of virus isolated from mosquitoes in the Philippines

Tanay virus, a new species of virus isolated from mosquitoes in the Philippines
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DOI:
10.1099/vir.0.061887-0
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发表时间:
2014-06-01
影响因子:
3.8
通讯作者:
Morita, Kouichi
Morita, Kouichi
中科院分区:
医学3区
文献类型:
--
作者:
Nabeshima, Takeshi;Inoue, Shingo;Morita, Kouichi

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2005年,我们从菲律宾的蚊子中分离出一种新的病毒。病毒粒子呈椭圆形,有一个较短的单一突起。该病毒被命名为塔奈病毒(TANAV),以其发现的地点命名。TANAV基因组RNA为9562 NT+PolyA正链,为多顺反子。最长的ORF含有推测的RNA依赖RNA聚合酶(RdRP);然而,RdRP中保守的短基序被置换。TANAV与NegeVirus、柑橘麻风病毒C、木槿花绿斑病毒、蓝莓坏死性环斑病毒等植物病毒的亲缘关系较近。本文描述了TANAV及其Rdrp的排列结构,并与植物病毒和新病毒的系统发育进行了讨论。
In 2005, we isolated a new species of virus from mosquitoes in the Philippines. The virion was elliptical in shape and had a short single projection. The virus was named Tanay virus (TANAV) after the locality in which it was found. TANAV genomic RNA was a 9562 nt+poly-A positive strand, and polycistronic. The longest ORF contained putative RNA-dependent RNA polymerase (RdRP); however, conserved short motifs in the RdRP were permuted. TANAV was phylogenetically close to Negevirus, a recently proposed taxon of viruses isolated from haemophagic insects, and to some plant viruses, such as citrus leprosis virus C, hibiscus green spot virus and blueberry necrotic ring blotch virus. In this paper, we describe TANAV and the permuted structure of its RdRP, and discuss its phylogeny together with those of plant viruses and negevirus.