The psychological state and changes in the routine of the patients with rheumatic diseases during the coronavirus disease (COVID-19) outbreak in Turkey: a web-based cross-sectional survey
The psychological state and changes in the routine of the patients with rheumatic diseases during the coronavirus disease (COVID-19) outbreak in Turkey: a web-based cross-sectional survey
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DOI：
10.1007/s00296-020-04626-0
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发表时间：
2020-06-22
影响因子：
4
通讯作者：
Hamuryudan, Vedat
中科院分区：
文献类型：
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作者：
Seyahi, Emire;Poyraz, Burc Cagri;Hamuryudan, Vedat
我们假设风湿病(RD)患者在新冠肺炎爆发期间会增加心理痛苦；因此，我们评估了他们的心理症状和日常生活中的变化。采用横断面设计对三组受试者进行了基于网络的问卷调查：(1)RD患者，(2)医院工作人员；(3)高中教师/教职员工。采用医院焦虑抑郁量表和事件影响量表-修订量表评估患者的精神状态。总有效率为34.7%。我们研究了771名RD患者、医院工作人员和917名教师/教职员工。大部分RD患者不愿意去医院(86%)，22%的患者停止用药。生物DMARDS是最常发生剂量变化的药物。只有4%的人愿意服用羟基氯喹作为保护措施。此外，RD患者的焦虑(20%)、抑郁(43%)和创伤后应激(28%)的发生率与教师/教职员工(分别为23%、43%和29%)相似，但显著低于医院工作人员(分别为40%、62%和46%)(p<；0.001)。在整个研究人群中，女性、使用社交媒体、患有共病或精神障碍与精神症状独立相关。大多数患者不愿去门诊，五分之一的患者跳过或停止服用免疫抑制剂。患者和教师群体中的精神症状在临床上引起了相当大的关注，尽管明显低于医院工作人员中观察到的。
We hypothesized that patients with rheumatic diseases (RD) would have increased psychological distress during the COVID-19 outbreak; therefore, assessed their psychological symptoms and changes in their routine. A web-based questionnaire survey was conducted in a cross-sectional design in three groups of participants: (1.) patients with RD, (2.) hospital workers, and (3.) high-school teachers/academic staff. Psychiatric status was evaluated using Hospital Anxiety and Depression Scale and Impact of Event Scale-Revised scale. Overall response rate was 34.7%. We studied 771 patients with RD, 535 hospital workers, and 917 teachers/academic staff. Most of the patients with RD were unwilling to go to the hospital (86%), while 22% discontinued their medications. Biological DMARDS were the most frequent drugs whose doses were altered. Only 4% were willing to take hydroxychloroquine for protection. Moreover, the frequency of anxiety (20%), depression (43%), and post-traumatic stress (28%) among patients with RD were found to be comparable to that found among the teachers/academic staff (23%, 43% and 29%, respectively), whereas significantly less than that observed among the hospital workers (40%, 62%, and 46%, respectively) (p < 0.001). Female gender, use of social media, having a comorbid disease, or a psychiatric disorder were found to be independently associated with psychiatric symptoms in total study population. The majority of the patients were unwilling to attend outpatient visits and one-fifth skipped or stopped their immunosuppressive agents. Psychiatric symptoms in patient's and teacher's populations were of considerable clinical concern, despite being significantly lower than that observed among the hospital workers.