Depression, disability days, and days lost from work in a prospective epidemiologic survey.
Depression, disability days, and days lost from work in a prospective epidemiologic survey.
复制标题
DOI：
10.1001/jama.1990.03450190056028
复制
发表时间：
1990-11
期刊：
影响因子：
--
通讯作者：
W. Broadhead;D. Blazer;L. George;C. Tse
中科院分区：
文献类型：
--
作者：
W. Broadhead;D. Blazer;L. George;C. Tse
我们对北卡罗来纳州流行病学流域研究的2980名参与者进行了为期1年的随访，描述了抑郁和抑郁症状与残疾天数和工作天数的关系。与无症状个体相比，重度抑郁症患者致残风险高4.78倍（95%可信区间，1.64 ~ 13.88），轻度抑郁症伴情绪障碍但非重度抑郁症患者致残风险高1.55倍（95%可信区间，1.00 ~ 2.40）。由于其普遍性，社区中患有轻度抑郁症的人比患有重度抑郁症的人多出51%的残疾天数。这组人在一年内患焦虑症或重度抑郁症的风险也增加了。我们的结论是，识别临床显著抑郁症的阈值可能需要重新评估，以包括症状较少但可测量的发病率的人。只有改变我们的疾病分类学，才能充分解决抑郁症的社会影响。
We describe the relationship of depression and depressive symptoms to disability days and days lost from work in 2980 participants in the Epidemiologic Catchment Area Study in North Carolina after 1 year of follow-up. Compared with asymptomatic individuals, persons with major depression had a 4.78 times greater risk of disability (95% confidence interval, 1.64 to 13.88), and persons with minor depression with mood disturbance, but not major depression, had a 1.55 times greater risk (95% confidence interval, 1.00 to 2.40). Because of its prevalence, individuals with minor depression were associated with 51% more disability days in the community than persons with major depression. This group was also at increased risk of having a concomitant anxiety disorder or developing major depression within 1 year. We conclude that the threshold for identifying clinically significant depression may need to be reevaluated to include persons with fewer symptoms but measurable morbidity. Only by changing our nosology can the societal impact of depression be adequately addressed.