Antibodies specific for the pancreatic islet amyloid polypeptide associated with type 2 diabetes mellitus.

Antibodies specific for the pancreatic islet amyloid polypeptide associated with type 2 diabetes mellitus.
复制标题

与 2 型糖尿病相关的胰岛淀粉样蛋白多肽特异性抗体。

DOI:
10.1016/0006-291x(89)90005-3
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发表时间:
1989
影响因子:
3.1
通讯作者:
Mehlhaff,P
Mehlhaff,P
中科院分区:
生物学4区
文献类型:
--
作者:
Glenner,GG;Ceja,F;Mehlhaff,P

文献摘要

被引文献

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Antibodies raised to a lysine solubilized peptide composed of residues 20–29 of the pancreatic islet amyloid polypeptide react selectively and specifically with this polypeptide and with islet amyloid deposits in Type 2 diabetes mellitus. These antibodies may prove useful in studies employing radioimmunoassay of body fluids and islet cell cultures in order to define if a pathogenic relationship exists between the islet amyloid polypeptide and Type 2 diabetes mellitus.