Biotransformation of dichloro-, trichloro-, and tetrachlorodibenzo-p-dioxin by the white-rot fungus Phlebia lindtneri
Biotransformation of dichloro-, trichloro-, and tetrachlorodibenzo-p-dioxin by the white-rot fungus Phlebia lindtneri
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DOI：
10.1007/s00253-005-1947-9
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发表时间：
2005-03
影响因子：
5
通讯作者：
Ichiro Kamei;R. Kondo
中科院分区：
文献类型：
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作者：
Ichiro Kamei;R. Kondo
以2，7-二氯、2，3，7-三氯、1，2，6，7-、1，2，8，9-和1，3，6，8-四氯二苯并二恶英（PCDDs）为模型物质，进行了白腐菌Phlebia lindtneri的降解实验。以2，7-二氯二苯并二恶英（2，7-diCDD）为原料，经生物转化得到羟基化和甲氧基化的diCDD。除1，3，6，8-四氯二苯并对二恶英外，其它三氯和四氯二苯并对二恶英均被P. lindtneri 1，2，6，7-四氯二苯并对二恶英的降解率高于2，3，7-三氯二苯并对二恶英，而1，3，6，8-四氯二苯并对二恶英没有降解。这些结果表明，这些PCDDs的降解取决于氯化模式的基板。这是首次报道的羟基化和甲氧基化的三到四-CDDs的真菌菌株。
The model polychlorinated dibenzo-p-dioxins (PCDDs) 2,7-dichloro-, 2,3,7-trichloro, 1,2,6,7-, 1,2,8,9-, and 1,3,6,8-tetrachlorodibenzo-p-dioxin were used as substrates for a degradation experiment with the white-rot fungusPhlebia lindtneri. 2,7-Dichlorodibenzo-p-dioxin (2,7-diCDD) was biotransformed to hydroxylated diCDD and methoxylated diCDD. With the exception of 1,3,6,8-tetrachlorodibenzo-p-dioxin, the tri- and tetrachlorodibenzo-p-dioxins were biotransformed to hydroxyl and methoxyl compounds byP. lindtneri. The degradation rate of 1,2,6,7-tetrachlorodibenzo-p-dioxin was higher than that of 2,3,7-trichlorodibenzo-p-dioxin and no degradation of 1,3,6,8-tetrachlorodibenzo-p-dioxin was observed. These results indicate that the degradation of these PCDDs depends on the chlorination patterns of the substrates. This is the first report of the hydroxylation and methoxylation of tri- to tetra-CDDs by a fungal strain.