The Effectiveness of Contact Precautions on Methicillin-Resistant Staphylococcus aureus in Long-term Care Across the United States.

The Effectiveness of Contact Precautions on Methicillin-Resistant Staphylococcus aureus in Long-term Care Across the United States.
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美国各地长期护理中针对耐甲氧西林金黄色葡萄球菌的接触预防措施的有效性。

DOI:
10.1093/cid/ciz1045
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发表时间:
2020
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Pineles,Lisa
Pineles,Lisa
中科院分区:
--
文献类型:
--
作者:
Morgan,DanielJ;Zhan,Min;Goto,Michihiko;Franciscus,Carrie;Alexander,Bruce;Vaughan-Sarrazin,Mary;Roghmann,Mary-Claire;Pineles,Lisa

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背景耐甲氧西林金黄色葡萄球菌(MRSA)是长期护理机构(LTCF)卫生保健相关感染的常见原因。疾病控制和预防中心建议在急性护理机构内预防MRSA的接触预防措施,这些措施正在美国退伍军人事务部(VA)以改良的方式用于LTCF。长期护理中接触预防措施的影响尚不清楚。MethodsTo评估接触预防措施是否能降低LTCF中MRSA的获得,与标准预防措施相比,我们进行了一项回顾性有效性研究,(前后,同时对照)使用VA医疗保健系统2011年1月1日至2015年12月31日的数据,2年之前和之后的2013年的政策,建议更积极的形式的接触precautions.ResultsAcross 75 414例患者入院从74个长期护理设施在美国,MRSA收购的整体未调整率为2.6/1000患者天。在一项多变量、离散时间生存分析中,控制患者人口统计学、危险因素和入院年份,(比值比,0.97; 95%置信区间,0.85 -1.12; P= .71)。结论MRSA的收购和感染并没有受到使用主动监测和接触预防措施在VA的LTCF。
BackgroundMethicillin-resistantStaphylococcus aureus(MRSA) is a common cause of health care–associated infections in long-term care facilities (LTCFs). The Centers for Disease Control and Prevention recommends contact precautions for the prevention of MRSA within acute care facilities, which are being used within the United States Department of Veterans Affairs (VA) for LTCFs in a modified fashion. The impact of contact precautions in long-term care is unknown.MethodsTo evaluate whether contact precautions decreased MRSA acquisition in LTCFs, compared to standard precautions, we performed a retrospective effectiveness study (pre-post, with concurrent controls) using data from the VA health-care system from 1 January 2011 until 31 December 2015, 2 years before and after a 2013 policy recommending a more aggressive form of contact precautions.ResultsAcross 75 414 patient admissions from 74 long-term care facilities in the United States, the overall unadjusted rate of MRSA acquisition was 2.6/1000 patient days. Patients were no more likely to acquire MRSA if they were cared for using standard precautions versus contact precautions in a multivariable, discrete time survival analysis, controlling for patient demographics, risk factors, and year of admission (odds ratio, 0.97; 95% confidence interval, .85–1.12;P= .71).ConclusionsMRSA acquisition and infections were not impacted by the use of active surveillance and contact precautions in LTCFs in the VA.
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