Partial Normalization of Biomarkers of Inflammation and Immune Activation Among Virally Suppressed Men With HIV Infection and High ART Adherence
Partial Normalization of Biomarkers of Inflammation and Immune Activation Among Virally Suppressed Men With HIV Infection and High ART Adherence
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DOI：
10.1093/ofid/ofaa099
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发表时间：
2020-04-01
影响因子：
4.2
通讯作者：
Wada, Nikolas I.
中科院分区：
文献类型：
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作者：
Castillo-Mancilla, Jose R.;Brown, Todd T.;Wada, Nikolas I.
背景本研究的目的是调查是否100%的抗逆转录病毒治疗（ART）坚持男性艾滋病毒（MWH）与正常化的浓度的生物标志物的炎症和免疫激活相比，HIV未感染的男子。我们分析了多中心艾滋病队列研究（MACS）中接受HIV RNA抗逆转录病毒治疗的MWH中可用生物标志物数据的访视人数
Background. The objective of this study was to investigate whether 100% antiretroviral therapy (ART) adherence in men with HIV (MWH) is associated with normalization of concentrations of biomarkers of inflammation and immune activation compared with HIV-uninfected men.Methods. We analyzed person-visits with available biomarker data from the Multicenter AIDS Cohort Study (MACS) among MWH receiving ART with HIV RNA