Benzodiazepine use in older adults enrolled in a health maintenance organization
Benzodiazepine use in older adults enrolled in a health maintenance organization
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DOI：
10.1176/appi.ajgp.11.5.568
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发表时间：
2003-09-01
影响因子：
7.2
通讯作者：
LaCroix, AZ
中科院分区：
文献类型：
--
作者：
Gray, SL;Eggen, AE;LaCroix, AZ
目的：作者研究了老年人苯二氮卓类药物的使用模式。具体而言，他们描述了指数年内苯二氮卓类药物使用的流行率和发生率，描述了4年内苯二氮卓类药物使用的持续性和强度;并检查了与来年苯二氮卓类药物使用相关的因素。作者对1986年至1992年在老年健康维护组织登记者中进行的健康促进干预试验中收集的数据进行了二次分析（N= 1，505）。苯二氮卓类药物的使用是从计算机药房记录中确定的。人口学特征，健康状况和健康行为通过邮寄问卷确定。结果：在指数年，苯二氮卓类药物的使用率和患病率分别为12.3%和6.6%。在指数年使用的用户中，16%的新用户和63%的以前用户在接下来的3年中继续使用。与苯二氮卓类药物使用在接下来的一年显着相关的因素是女性性别，高中教育，较高的慢性病评分，较高水平的自我报告的疼痛和压力，低至正常的身体质量指数（BMI），和自我报告的神经障碍结论：新用户坏低强度的使用和低概率继续使用在接下来的3年。这个样本中有一小部分是4年来每天使用的不良证据。值得关注的是，样本中髋部骨折风险最大的部分（BMI正常/低的女性）使用了苯二氮卓类药物。临床医生应定期评估是否需要继续使用苯二氮卓类药物。
Objectives: The authors examined patterns of benzodiazepine use in older adults. Specifically, they describe prevalence and incidence of benzodiazepine use during the index year, describe persistence and intensity of benzodiazepine use over a 4-year period; and examine factors associated with benzodiazepine use in the upcoming year Methods: Authors performed a secondary analysis of data collected as part of a health promotion intervention trial conducted from 1986 to 1992 in older health maintenance organization enrollees (N=1,505). Benzodiazepine use was ascertained from computerized pharmacy records. Demographic characteristics, health status, and health behaviors were ascertained from mailed questionnaires. Results: During the index year, the prevalence and incidence of benzodiazepine use was 12.3% and 6.6%, respectively. Of those using during the index year, 16% of new users and 63% of previous users continued to use for the following 3 years. The factors significantly associated with benzodiazepine use in the following year were female gender, high school education, higher chronic disease score, higher levels of self-reported pain and stress, low-to-normal body mass index (BMI), and self-reported nervous disorder Conclusions: New users bad low intensity of use and a low probability of continuing use over the following 3 years. A very small percentage of this sample bad evidence of daily use for 4 years. Of concern, benzodiazepines were used by the segment of the sample that were at greatest risk for hip fractures (women with normal/low BMI). Clinicians should assess the need for continued benzodiazepine use at regular intervals.