Congenital Brucellosis in an Infant
Congenital Brucellosis in an Infant
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DOI：
10.1089/vbz.2012.1165
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发表时间：
2013-07-01
影响因子：
2.1
通讯作者：
Lucero, Nidia E.
中科院分区：
文献类型：
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作者：
Cacace, Maria L.;Claros, Erica A.;Lucero, Nidia E.
据报道，布鲁氏菌病主要发生在孕妇中，它可能导致自然流产、宫内胎儿死亡或分娩受感染的新生儿。通过母乳传播也有报道，但先天性病例不常报道。我们提出的临床发现，实验室研究，治疗，并最终结果产前晚期传播从母亲到她的足月婴儿布鲁氏菌生物品种1。由于缺乏临床怀疑，母体疾病未被发现，只能通过婴儿血液培养结果进行诊断。误诊不明原因发热（FUO）的鉴别诊断可能导致，如本病例，给予不适当的抗菌药物治疗。应提醒初级卫生保健医生注意这种感染的临床和实验室结果，在布鲁氏菌病仍然存在问题的地区，应定期对孕妇进行血清学检测。
Brucellosis has been reported mainly among pregnant women, and it may lead to spontaneous abortion, intrauterine fetal death, or delivery of an infected neonate. Transmission through breast milk has also been described, but congenital cases are not commonly reported. We present the clinical findings, laboratory studies, treatment, and final outcome of a late prenatal transmission from a mother to her term infant of Brucella melitensis biovar 1. Because the maternal disease was undetected due to lack of clinical suspicion, diagnosis was made possible only by the results of infant blood cultures. Differential diagnosis of fever of unknown origin (FUO) misdiagnosed could result, as in our case, in the administration of inappropriate antimicrobial therapy. Primary health care physicians should be alerted to the clinical and laboratory findings of this infection, and pregnant women should routinely be tested serologically in areas where brucellosis is still a problem.