Radiological and clinical outcomes of balloon kyphoplasty for osteoporotic vertebral compression fracture in patients with rheumatoid arthritis.
Radiological and clinical outcomes of balloon kyphoplasty for osteoporotic vertebral compression fracture in patients with rheumatoid arthritis.
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类风湿关节炎患者的骨质疏松性椎骨压缩性骨折的球囊脑膜成形术的放射学和临床结果。
DOI：
10.1186/s13018-021-02573-5
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发表时间：
2021-07-06
影响因子：
2.6
通讯作者：
Jia Y
中科院分区：
文献类型：
--
作者：
Guo J;Zhai W;Wei L;Zhang J;Jin L;Yan H;Huang Z;Jia Y
本研究旨在探讨球囊后凸成形术（KP）治疗类风湿关节炎（RA）患者骨质疏松性椎体压缩性骨折（OVCF）的疗效和并发症，并与非RA的OVCF患者比较其影像学和临床效果。RA组98例158节椎骨骨折，对照组114例150节椎骨骨折。观察KP术后压缩率、局部后凸角、视觉模拟评分（VAS）、Oswestry失能指数（ODI）评分、骨水泥渗漏情况、手术椎体再骨折情况、相邻椎体新骨折情况的变化。此外，根据红细胞沉降率（ESR）、c反应蛋白（CRP）值以及是否使用糖皮质激素，将RA组患者分为不同的组，以评估其对KP结局的影响。KP手术显著改善了RA组和对照组的压缩率、局部后凸角、VAS和ODI评分（p<0.05）。RA组压缩率和局部后凸角度的变化明显大于对照组（p<0.05），且RA患者在KP后发生更多新的相邻椎体骨折。不同ESR组和CRP组KP的预后和并发症无明显差异。使用糖皮质激素的RA患者骨水泥渗漏发生率明显高于未使用糖皮质激素的RA患者。此外，使用糖皮质激素的RA患者更容易发生椎间盘内渗漏和新的相邻椎体骨折。与没有RA的OVCF患者相比，合并RA的OVCF患者在KP后压缩率和局部后凸角方面有更大的改善，但他们发生了更多新的相邻椎体骨折。在使用糖皮质激素的RA患者中，椎间盘内渗漏和新的相邻椎体骨折发生率更高。回顾注册。
This study was conducted to investigate the outcomes and complications of balloon kyphoplasty (KP) for the treatment of osteoporotic vertebral compression fracture (OVCF) in patients with rheumatoid arthritis (RA) and compare its radiological and clinical effects with OVCF patients without RA. Ninety-eight patients in the RA group with 158 fractured vertebrae and 114 patients in the control group with 150 vertebrae were involved in this study. Changes in compression rate, local kyphotic angle, visual analog scale (VAS) and Oswestry disability index (ODI) scores, conditions of bone cement leakage, refracture of the operated vertebrae, and new adjacent vertebral fractures were examined after KP. In addition, patients in the RA group were divided into different groups according to the value of erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), and whether they were glucocorticoid users or not to evaluate their influence on the outcomes of KP. KP procedure significantly improved the compression rate, local kyphotic angle, and VAS and ODI scores in both RA and control groups (p<0.05). Changes in compression rate and local kyphotic angle in the RA group were significantly larger than that in the control group (p<0.05), and patients with RA suffered more new adjacent vertebral fractures after KP. The outcomes and complications of KP from different ESR or CRP groups did not show significant differences. The incidence of cement leakage in RA patients with glucocorticoid use was significantly higher than those who did not take glucocorticoids. In addition, RA patients with glucocorticoid use suffered more intradiscal leakage and new adjacent vertebral fractures. OVCF patients with RA obtained more improvement in compression rate and local kyphotic angle after KP when compared to those without RA, but they suffered more new adjacent vertebral fractures. Intradiscal leakage and new adjacent vertebral fractures occurred more in RA patients with glucocorticoid use. Retrospectively registered.
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影响因子：
4
作者：
Ghazi, M.;Kolta, S.;Roux, C.
通讯作者：
Roux, C.
影响因子：
3
作者：
Ledlie, JT;Renfro, MB
通讯作者：
Renfro, MB
影响因子：
4
作者：
Liu, J. T.;Liao, W. J.;Lin, T. B.
通讯作者：
Lin, T. B.
影响因子：
2.3
作者：
Lee JH;Sung YK;Choi CB;Cho SK;Bang SY;Choe JY;Hong SJ;Jun JB;Kim TH;Lee J;Lee HS;Yoo DH;Yoon BY;Bae SC
通讯作者：
Bae SC
影响因子：
2.8
作者：
Lovi, Alessio;Teli, Marco;Brayda-Bruno, Marco
通讯作者：
Brayda-Bruno, Marco