Developmental aspects of obsessive compulsive disorder: Findings in children, adolescents, and adults
Developmental aspects of obsessive compulsive disorder: Findings in children, adolescents, and adults
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DOI：
10.1097/00005053-200107000-00009
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发表时间：
2001-07-01
影响因子：
1.9
通讯作者：
Coffey, BJ
中科院分区：
文献类型：
--
作者：
Geller, DA;Biederman, J;Coffey, BJ
虽然青少年强迫症（OCD）越来越多地被认为是一种公认的发展亚型的障碍，比较儿童，青少年和成人与强迫症一直缺乏。我们的目的是评估临床相关的强迫症在三个发展不同的群体。受试者包括符合DSM-HI-R和DSM-IV强迫症标准的儿童、青少年和成年人，他们被转诊到单独的专门强迫症诊所。所有受试者均由OCD专家通过结构化诊断访谈和临床评估进行系统评估。特定的临床相关因素和症状特征与不同年龄组的疾病相关。这些研究结果支持了青少年和成人强迫症之间的发展不连续性的假设，并确定了整个生命周期的疾病的年龄特异性相关性。需要进一步的工作来验证青少年发作的强迫症是否代表了这种疾病的真正发育亚型。
Although juvenile, obsessive compulsive disorder (OCD) is increasingly recognized as a putative developmental subtype of the disorder, comparisons among children, adolescents, and adults with OCD have been lacking. We aimed to evaluate clinical correlates of OCD in three developmentally distinct groups. Subjects comprised children, adolescents, and adults meeting DSM-HI-R and DSM-IV criteria for OCD referred to separate specialized OCD clinics. All subjects were systematically evaluated with structured diagnostic interviews and clinical assessments by OCD experts. Specific clinical correlates and symptom profiles were associated with the disorder in different age groups. These findings support a hypothesis of developmental discontinuity between juvenile and adult OCD and identify age specific correlates of the disorder across the life cycle. Further work is needed to validate whether juvenile-onset OCD represents a true developmental subtype of the disorder.