Atrophy of the Stria Vascularis.
Atrophy of the Stria Vascularis.
复制标题
血管纹萎缩。
DOI：
10.1097/mao.0000000000000935
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
LinthicumJr,FredH
中科院分区：
文献类型：
--
作者：
Peng,KevinA;LinthicumJr,FredH
血管纹产生内淋巴并通过主动转运维持耳蜗内电位，对声音的机械电传导至关重要（1）。血管纹萎缩被认为是遗传因素影响的结果，典型的结果是进行性双侧对称感觉神经缺失，呈扁平状[3]。在本例中，一名女性患者因右侧慢性中耳炎而到耳科诊所接受手术治疗。在12年的过程中，进行了一系列听力检查，发现对称的，进行性恶化的骨传导阈值与血管纹萎缩一致。这一点在尸检中得到证实。虽然并不罕见，但血管纹性听力损失可能是老年性耳聋的一个未被认识到的原因。
DISCUSSIONThe stria vascularis, which produces endolymph and maintains the endocochlear potential via active transport, is essential for the mechanoelectrical transduction of sound (1). Atrophy of the stria vascularis, which is thought to be genetically influenced, classically results in a progressive, bilateral symmetric sensorineural loss in a flat configuration (3).In this case, a female patient presented to the otology clinic for surgical management of right-sided chronic otitis media. Over the course of 12 years, serial audiometric examination was performed, revealing symmetric, progressively worsening bone conduction thresholds consistent with atrophy of the stria vascularis. This was confirmed on postmortem examination. Although not uncommon, stria vascularis hearing loss likely represents an underrecognized cause of presbycusis.