Resection of peritoneal implantation from hepatocellular carcinoma
Resection of peritoneal implantation from hepatocellular carcinoma
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肝细胞癌腹膜种植切除术
DOI：
10.1007/bf02557522
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发表时间：
2002
影响因子：
3.7
通讯作者：
L. Jen
中科院分区：
文献类型：
--
作者：
C. Yeh;Miin‐Fu Chen;L. Jen
背景肝细胞癌（HCC）腹膜种植是一种罕见的表现。本文介绍了16例发现肝癌孤立性腹膜种植并接受手术切除的肝癌患者的临床特征和手术结果。方法从1988年到2000年，回顾性分析16例肝切除术后肝癌患者行肝癌腹膜种植切除术的临床资料。肝癌切除术后复发率为62.1%。16例（3.4%）发生孤立性腹膜种植并接受切除。在检测腹膜种植过程中，16例患者中有13例甲胎蛋白水平升高。15例患者中有5例通过超声检查发现腹膜肿块，15例患者中有14例通过计算机断层扫描发现肿块。随访时间范围为2.1至81.6个月（中位数，16个月）。16例患者的中位无病生存期和总生存期分别为7.89和15.98个月，分别为。肝切除术后甲胎蛋白升高提示肝癌复发。CT在检测HCC腹膜种植方面优于超声波检查，但CT在这方面有上级优势。手术切除肝癌腹膜种植可能延长选定患者的生存期。
BackgroundPeritoneal implantation is a rare presentation of hepatocellular carcinoma (HCC). This article presents the clinical features and surgical outcomes of 16 patients with HCC in whom isolated peritoneal implantation from HCC was found and who underwent surgical resection.MethodsFrom 1988 to 2000, 16 patients with HCC after hepatic resection who underwent resection of peritoneal implantation of HCC were retrospectively reviewed.ResultsFour hundred sixty-five of 749 patients (62.1%) had recurrence of HCC after heptic resection. Sixteen (3.4%) developed isolated peritoneal implantation and underwent resection. During the detection of the peritoneal implantation, the alfa fetoprotein level was increased in 13 of these 16 patients. Five of 15 patients had a peritoneal mass discovered by ultrasonography, and 14 of 15 patients had a mass discovered by computed tomography. The follow-up period ranged from 2.1 to 81.6 months (median, 16 months). The median disease-free and overall survivals of the 16 patients were 7.89 and 15.98 months, respectively.ConclusionsPeritoneal implantation occurs infrequently in posthepatectomy patients. Increased alfa fetoprotein values after hepatic resection should suggest recurrence of HCC. Computed tomography is superior to ultrasonography in detection of peritoneal implantation from HCC. Surgical resection of peritoneal implantation from HCC might prolong survival in selected patients.
DOI：
10.1007/978-4-431-68177-9
发表时间：
1992-11
期刊：
Gann monograph on cancer research
影响因子：
--
作者：
S. Arii;T. Tobe
通讯作者：
S. Arii;T. Tobe