Distant echoes of the accordion: Reduced dimensionality, GFT-NMR, and projection-reconstruction of multidimensional spectra
Distant echoes of the accordion: Reduced dimensionality, GFT-NMR, and projection-reconstruction of multidimensional spectra
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DOI：
10.1002/cmr.a.20021
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发表时间：
2004-11-01
影响因子：
0.6
通讯作者：
Kupce, E
中科院分区：
文献类型：
--
作者：
Freeman, R;Kupce, E
多维核磁共振光谱学可以通过减少独立检查的演化周期的数量的技术来明显加快。本文综述了从手风琴实验开始的“降维”概念的演变，并展示了它如何逐渐发展成为GFT-NMR和投影重建（PR-NMR），它收集不同方向的平面投影，并使用它们来重建完整的多维光谱。虽然GFT-NMR和PR-NMR的数据收集阶段相似，但处理阶段完全不同。这里描述的方法通常适用于标准的多维NMR序列，它们提供了相当的灵敏度和分辨率，以及类似的速度优势。通过采用与逆Radon变换相关的方法，PR-NMR也可以应用于仅具有边缘灵敏度的情况。(C)2004 Wiley Periodicals，Inc.
Multidimensional NMR spectroscopy can be speeded up appreciably by techniques that reduce the number of evolution periods examined independently. This review charts the evolution of the "reduced dimensionality" concept starting with the accordion experiment, and showing how it gradually developed into GFT-NMR and projection-reconstruction (PR-NMR), which collects plane projections at different orientations and uses them to reconstruct the full multidimensional spectrum. While the data-gathering stages of GFT-NMR and PR-NMR are similar, the processing stages are radically different. The methods described here are generally applicable to the standard multidimensional NMR sequences, and they offer comparable sensitivity and resolution, and a similar advantage in speed. By adopting a method related to the inverse Radon transform, PR-NMR can also be applied to situations of only marginal sensitivity. (C) 2004 Wiley Periodicals, Inc.