Contact stomatitis due to methyl methacrylate monomer
Contact stomatitis due to methyl methacrylate monomer
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甲基丙烯酸甲酯单体引起的接触性口腔炎
DOI：
10.1111/j.1600-0536.1989.tb03125.x
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发表时间：
1989
影响因子：
5.5
通讯作者：
Koji Isayama
中科院分区：
文献类型：
--
作者：
T. Kanzaki;Y. Kabasawa;T. Jinno;Koji Isayama
没食子酸丙酯是一种无味、“无毒”的抗氧化剂，自1947年以来一直在商业上使用。一名58岁的女性报告了由没食子酸丙酯引起的口红皮炎（2）。在各种局部制剂中也报告了接触敏感性，包括AlphosyJ®霜（没食子酸丙酯0.015%）（3）、Idomin Fukt®护手霜（没食子酸丙酯0.006%）（4）地莫环素软膏（5）（没食子酸丙酯0.1%）和。“身体和婴儿护理乳液”（6）。人造黄油、黄油和精油是没食子酸丙酯的常见来源，经常与其他没食子酸酯（辛基，Iauury！）。对没食子酸盐的接触致敏被描述为面包店和餐饮业的职业危害（4，7，8，9）。局部没食子酸丙酯（20%）是豚鼠中的一种强效接触致敏剂，可在先前致敏的豚鼠中诱导特异性反应不良（10）。卡恩等我！(10)用没食子酸丙酯致敏10名成人志愿者中的5名（20%）。他们推测，是否缺乏报告的敏感性，在男子，无论是在职业和家庭的情况下，是由于类似的反应迟钝引起的饮食中的没食子酸丙酯的消费。关于没食子酸丙酯接触敏感性的总体发生率，尚无准确数据。在200例皮炎患者中，有8例对没食子酸丙酯I%的阳性反应（11）;然而，这些反应被认为是刺激性的，与他们目前的皮炎无关。在最近的2项研究中，40例对照受试者未获得阳性反应（4，6）。简短的交流
Propyl gallate is a tasteless, 'non-toxic' antioxidant, used commercially since 1947. Lipstick dermatitis due to propyl gallate has been described in a 58year-old woman (2). Contact sensitivity has also been reported in various topical preparations, including AlphosyJ® cream (propyl gallate 0.015%) (3), Idomin Fukt® hand cream (propyl gallate 0.006%) (4) democycline ointment (5) (propyl gallate 0.1 %) and. a "lotion for care of the body and babies" (6). Margarine, butter and essential oils are common sources of propyl gallate, frequently combined with other gallate esters (octy!, Iaury!). Contact sensitization to gallates has been described as an occupational hazard in the bakery and catering trades (4, 7, 8, 9). Topical propyl gallate (20%) is a potent contact sensitizer in the guinea pig and specific unreponsiveness can be induced in previously-sensitized guinea pigs (10). Kahn eta!. (10) sensitized 5 out of 10 adult human volunteers with propyl gallate (20%). They speculate as to whether the lack of reports of sensitivity in man, both in occupational and domestic situations, is due to a similar unresponsiveness induced by the consumption of propyl gallate in the diet. There are no accurate data as to the overall incidence of contact sensitivity to propyl gallate. There were 8 positive reactions to propyl gallate I% in 200 consecutive patients with dermatitis (11); however, these were thought to be irritant and not relevant to their current dermatitis. No positive reactions were obtained in 40 control subjects in 2 recent studies (4, 6). SHORT COMMUNICATIONS