Daintain/AIF-1 Reinforces the Resistance of Breast Cancer Cells to Cisplatin

Daintain/AIF-1 Reinforces the Resistance of Breast Cancer Cells to Cisplatin
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Daintain/AIF-1 增强乳腺癌细胞对顺铂的抵抗力

DOI:
10.1271/bbb.120577
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发表时间:
2012-12-01
影响因子:
1.6
通讯作者:
Chen, Zhengwang
Chen, Zhengwang
中科院分区:
工程技术4区
文献类型:
--
作者:
Jia, Shaohui;Chaibou, Moctar Ali;Chen, Zhengwang

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Our previous studies revealed that daintain/AIF-1 promoted the proliferation and migration of breast cancer cells. In the present study, we investigated the effect of daintain/AIF-1 on the cisplatin resistance of breast cancer cells. The results indicated that daintain/AIF-1 reinforced the resistance of breast cancer cells to cisplatin by inhibition of cell apoptosis and reduction of intracellular cisplatin accumulation.