ACQUIRED INFLAMMATORY DEMYELINATING POLYNEUROPATHIES - CLINICAL AND ELECTRODIAGNOSTIC FEATURES
ACQUIRED INFLAMMATORY DEMYELINATING POLYNEUROPATHIES - CLINICAL AND ELECTRODIAGNOSTIC FEATURES
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DOI：
10.1002/mus.880120602
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发表时间：
1989-06-01
期刊：
影响因子：
3.4
通讯作者：
KELLY, JJ
中科院分区：
文献类型：
--
作者：
ALBERS, JW;KELLY, JJ
获得性脱髓鞘性多发性神经病包括急性（AIDP，Guillain-Barré综合征，GBS）和慢性（CIDP，异常蛋白血症）形式，其主要区别在于其时间分布。它们是周围神经系统的炎性脱髓鞘疾病，可能具有免疫学发病机制。虽然这些神经病通常有一个特征性的表现，肌电图仪在他们的识别中起着核心作用，因为神经病的脱髓鞘成分，这大大减少了鉴别诊断，往往是在肌电图实验室首先确定。在AIDP中，肌电图仪除了确定诊断外，有时还可以预测预后。认识到慢性和异常蛋白血症形式的获得性脱髓鞘性多发性神经病是重要的，因为它们是可治疗的。异常蛋白血症形式也可能与也可能需要治疗的隐匿性全身性疾病相关，与神经病无关。
The acquired demyelinating polyneuropathies include acute (AIDP, Guillain‐Barré syndrome, GBS) and chronic (CIDP, dysproteinemic) forms which differ primarily in their temporal profile. They are inflammatory‐demyelinating diseases of the peripheral nervous system and likely have an immunologic pathogenesis. Although these neuropathies usually have a characteristic presentation, the electromyographer plays a central role in their recognition, since the demyelinating component of the neuropathy, which greatly reduces the differential diagnosis, is often first identified in the electromyography laboratory. In AIDP, the electromyographer, in addition to establishing the diagnosis, can sometimes predict the prognosis. Recognition of the chronic and dysproteinemic forms of acquired demyelinating polyneuropathy is important since they are treatable. The dysproteinemic forms also may be associated with occult systemic disorders that also may require treatment, independent of the neuropathy.