A SIMPLE ALTERNATIVE ANALYSIS FOR THRESHOLD DATA DETERMINED BY ASCENDING FORCED-CHOICE METHODS OF LIMITS
A SIMPLE ALTERNATIVE ANALYSIS FOR THRESHOLD DATA DETERMINED BY ASCENDING FORCED-CHOICE METHODS OF LIMITS
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DOI：
10.1111/j.1745-459x.2009.00262.x
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发表时间：
2010-06-01
影响因子：
2
通讯作者：
Lawless, Harry T.
中科院分区：
文献类型：
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作者：
Lawless, Harry T.
对强制选择阈值数据集（例如由 ASTM 方法 E-679 生成的类型）的另一种分析涉及机会校正 50% 检测的简单插值。这种分析有几个潜在的优点。该分析不需要使用临时启发式方法来估计高于和低于该系列的各个阈值。它考虑了正确猜测的可能性，而 ASTM 计算中并未考虑这一点，因此对估计值产生向下偏差。它不会折扣系列早期的正确响应，这些响应可能是合法的检测，但如果随后有任何不正确的响应，则 ASTM 方法会折扣。在一项大型消费者气味检测阈值研究数据集中对两种方法进行比较，得出了可比较的值。还可以进行插值以确定其他检测水平（例如 10%、25%）。 50% 以外的这些值可能有助于制定水或空气污染限制的监管标准，或者对于希望避免被更敏感的个体检测到污染的食品制造商而言可能有用。实际应用阈值估计的强制选择方法已被证明在比较各种风味物质的效力和比较个体的敏感性方面实际上有用。 ASTM 方法 E-679 就是此类方法之一。此处概述的该过程结果的替代分析提供了附加信息，并且不会因正确猜测而表现出向下偏差。
An alternative analysis of forced-choice threshold data sets such as the type generated by ASTM method E-679 involves a simple interpolation of chance-corrected 50% detection. This analysis has several potential advantages. The analysis does not require the ad hoc heuristics for estimating individual thresholds above and below the series. It takes into account the possibility of guessing correctly, which is not considered in the ASTM calculations and produces a downward bias to the estimates. It does not discount correct responses early in the series which may be legitimate detections, but which are discounted by the ASTM method if followed by any incorrect response. Comparisons of the two methods in a large consumer study of odor detection threshold study data set gave comparable values. The interpolation can also be done to determine other levels of detection (e.g. 10, 25%). These values other than 50% can be potentially useful in setting regulatory standards for water or air pollution limits or to food manufacturers who wish to avoid detection of taints by more sensitive individuals.PRACTICAL APPLICATIONSThe forced choice methods for threshold estimation have proven practically useful in comparing the potency of various flavor materials and in comparing the sensitivities of individuals. The ASTM method E-679 is one such method. The alternative analysis of results from this procedure which is outlined here provides additional information and does not exhibit the downward bias because of correct guessing.